Ahcène Boumendjel

Full Professor

Université Grenoble Alpes

France

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About

Ahcène Boumendjel is a Full Professor at Université Grenoble Alpes in France. His research focuses on various aspects of medicinal chemistry, including drug discovery, biochemical studies of membrane proteins, and the interaction of natural compounds with biological systems. Recent articles highlight his work on skin care applications of Garcinia kola, the synthesis of novel inhibitors, and the study of the endocannabinoid system. He employs advanced methodologies such as machine learning to further explore these complex interactions.

Articles (19)

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2025

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2020

Collaborators (10)

Marc Le Borgne

Professeur des Universités

Université Claude Bernard Lyon 1 - Domaine de Rockefeller

FRANCE

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Elisabetta Bergantino

ITALY

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Viet-Khoa Tran-Nguyen

Assistant Professor (MCF)

Université Paris Cité

FRANCE

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Luigi Bubacco

Full Professor

University of Padua

ITALY

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Laura Goracci

Associate Professor

University of Perugia

ITALY

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Suresh Ambudkar

Assistant Professor

Johns Hopkins University School of Medicine

UNITED STATES

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Joachim Jose

Full Professor (W3), Chair

Westfälische Wilhelms-Universität Münster

GERMANY

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Thales Kronenberger

GERMANY

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Catherine Belle

Université Grenoble Alpes

FRANCE

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Antti Poso

Professor at University of Eastern Finland

University of Eastern Finland

FINLAND

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Ahcène Boumendjel

Research Interests

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Articles (19)

Garcinia kola Nuts: A Molecular Cocktail for Skin Care

Assembly of Detergents with Highly Branched Dicarboxylate Clamps for Membrane Protein Studies

Ligand-Based Drug Discovery Leveraging State-of-the-Art Machine Learning Methodologies Exemplified by Cdr1 Inhibitor Prediction

Effects of Cholesterol on the Breast Cancer Resistance Protein: Studies through the Synthesis and Biological Evaluation of Chemical Tools

A novel quinone biosynthetic pathway illuminates the evolution of aerobic metabolism

One-step synthesis of diaryloxadiazoles as potent inhibitors of BCRP

Linking the Autotaxin-LPA Axis to Medicinal Cannabis and the Endocannabinoid System

Discovery of potent chromone-based autotaxin inhibitors inspired by cannabinoids

Incompatibility of Y-site-administered drugs: the case of acyclovir and ciprofloxacin

Inhibitors of ABCG2-mediated multidrug resistance: Lead generation through computer-aided drug design

Characterization of Potent ABCG2 Inhibitor Derived from Chromone: From the Mechanism of Inhibition to Human Extracellular Vesicles for Drug Delivery

New coumarin derivatives accessible in short and eco-friendly conditions with antifungal activity

Determination of the Relationship between the Granulometry and Release of Polyphenols Using LC-UV, and Their Antioxidant Activity of the Pulp Powder of the Moroccan Argan Tree, “Argania spinosa L.”

The first ADC bearing the ferroptosis inducer RSL3 as a payload with conservation of the fragile electrophilic warhead

Energetic Bio-Activation of Some Organic Molecules and Their Antioxidant Activity in the Pulp of the Moroccan Argan Tree «Argania spinosa L.»

Chemically Modified Extracellular Vesicles and Applications in Radiolabeling and Drug Delivery

Ditopic Chelators of Dicopper Centers for Enhanced Tyrosinases Inhibition

Diversity-Oriented Synthesis: Amino Acetophenones as Building Blocks for the Synthesis of Natural Product Analogs

Two in one: bifunctional derivatives of trolox acting as antimalarial and antioxidant agents

Collaborators (10)

Marc Le Borgne

Elisabetta Bergantino

Viet-Khoa Tran-Nguyen

Luigi Bubacco

Laura Goracci

Suresh Ambudkar

Joachim Jose

Thales Kronenberger

Catherine Belle

Antti Poso

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