Laura Goracci

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Associate Professor

University of Perugia

Italy

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About

Laura Goracci is an Associate Professor at the University of Perugia, Italy. Her research focuses on lipidomics, with recent articles exploring topics such as lipid profiling in mitochondrial fatty acid disorders, lipid signatures in vascular diseases, and the effects of various compounds on cell lipidomes. She also investigates the solubility and lipophilicity of PROTACs and contributes to the development of novel therapeutic strategies against SARS-CoV-2.

Recent Grants

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Exploring phospholipidosis induced by drugs and their metabolites

Open Date: 2012-09-01

Close Date: 2015-09-01

Articles (21)

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2022

Collaborators (17)

Maria Rosario Domingues

Universidade de Aveiro

PORTUGAL

Laura Goracci

Research Interests

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About

Recent Grants

Articles (21)

Lipidomic Profiling of Red Blood Cells in the Mitochondrial Fatty Acid β-oxidation Disorder MCADD Reveals Phospholipid and Sphingolipid Dysregulation

Lipidomic Signature of Abdominal Aortic Aneurysm and Peripheral Artery Disease

A lipidomic approach towards identifying the effects of fragrance hydroperoxides on keratinocytes

Unmasking the lipid landscape: carbamazepine induces alterations in Leydig cell lipidome

Between Theory and Practice: Computational/Experimental Integrated Approaches to Understand the Solubility and Lipophilicity of PROTACs

Discovery and Structure–Activity Relationships of Novel ssDAF-12 Receptor Modulators

Design, synthesis, and biological evaluation of first-in-class indomethacin-based PROTACs degrading SARS-CoV-2 main protease and with broad-spectrum antiviral activity

MARS: A Multipurpose Software for Untargeted LC–MS-Based Metabolomics and Exposomics

Use of ionic liquids in amidation reactions for proteolysis targeting chimera synthesis

Whole Blood and Plasma-Based Lipid Profiling Reveals Distinctive Metabolic Changes in Systemic Lupus Erythematosus and Systemic Sclerosis

Investigating Performance of the SLIM-Based High Resolution Ion Mobility Platform for Separation of Isomeric Phosphatidylcholine Species

VHL-Modified PROteolysis TArgeting Chimeras (PROTACs) as a Strategy to Evade Metabolic Degradation in In Vitro Applications

MassChemSite for In-Depth Forced Degradation Analysis of PARP Inhibitors Olaparib, Rucaparib, and Niraparib

Metals and organic species associated with fine and coarse aerosol particles in an electronic waste recycling plant

Guiding the choice of informatics software and tools for lipidomics research applications

Inhibitors of ABCG2-mediated multidrug resistance: Lead generation through computer-aided drug design

Software and Computational Tools for LC-MS-Based Epilipidomics: Challenges and Solutions

New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action

Metabolic Stability of Eight Airborne OrganoPhosphate Flame Retardants (OPFRs) in Human Liver, Skin Microsomes and Human Hepatocytes

Untargeted Screening of Per- and Polyfluoroalkyl Substances (PFASs) in Airborne Particulate of Three Italian E-Waste Recycling Facilities

Retinoic acid-induced 1 gene haploinsufficiency alters lipid metabolism and causes autophagy defects in Smith-Magenis syndrome

Collaborators (17)

Maria Rosario Domingues

Jose Manuel Paredes

serena rinaldo

Daniel D'Andrea

Ahcène Boumendjel

Franco Lucarelli

Claire O'Donovan

Marc Le Borgne

Simone Moretti

Javier Valverde-Pozo

Andrea Carotti

Ismael Zamora

Elisabetta Bucaletti

Ana S. P. Moreira

Robert Ahrends

Antimo Gioiello

Joachim Jose

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