Alan Cowman

University of Melbourne

Australia

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Articles (10)

Year:

2024

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Collaborators (7)

Kelly L. Rogers

Laboratory Head, Dynamic Imaging & Centre Manager

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Laura Dagley

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Wilson Wong

Research Group Head

Hudson Institute of Medical Research

AUSTRALIA

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Mikha Gabriela

University of Melbourne

AUSTRALIA

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Justin Boddey

Laboratory Head/Associate Professor

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Simon Draper

University of Oxford

UNITED KINGDOM

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Jeremy Burrows

VP, Head of Discovery

SWITZERLAND

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Alan Cowman

Research Interests

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Articles (10)

Flp/ FRT -mediated disruption of ptex150 and exp2 in Plasmodium falciparum sporozoites inhibits liver-stage development

Plasmepsin X activates the PCRCR complex of Plasmodium falciparum by processing PfRh5 for erythrocyte invasion

RH5.1-CyRPA-Ripr antigen combination vaccine shows little improvement over RH5.1 in a preclinical setting.

Nanobodies against Pfs230 block Plasmodium falciparum transmission

Substrate Peptidomimetic Inhibitors of P. falciparum Plasmepsin X with Potent Antimalarial Activity

RhopH2 and RhopH3 export enables assembly of the RhopH complex on P. falciparum-infected erythrocyte membranes

Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax

Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362

Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria

PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum

Collaborators (7)

Kelly L. Rogers

Laura Dagley

Wilson Wong

Mikha Gabriela

Justin Boddey

Simon Draper

Jeremy Burrows

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