Alan Ramsay

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King’s College London

United Kingdom

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Recent Grants

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Understanding how immunomodulatory drugs affect tumour microenvironment (TME)/CAF-driven immune suppression (lymphoma).

Open Date: 2016-01-01

Close Date: 2020-01-01

Grant: Close

Predicting Clinical Outcome After Traditional and Ibrutinib-based Therapy In Chronic Lymphocytic Leukemia

Open Date: 2015-05-19

Close Date: 2020-04-30

Grant: Close

Predicting Clinical Outcome After Traditional and Ibrutinib-based Therapy In Chronic Lymphocytic Leukemia

Open Date: 2015-05-01

Close Date: 2020-04-01

Grant: Close

Combinatorial immune checkpoint blockade in B-cell malignancy (CLL, lymphoma).

Open Date: 2015-01-01

Close Date: 2019-01-01

Grant: Close

Investigating the immunomodulatory role of cancer-associated fibroblasts (CAFs) in chronic lymphocytic leukemia

Open Date: 2014-11-01

Close Date: 2018-11-30

Articles (17)

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2025

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2021

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2021

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2020

Collaborators (18)

Esteban Braggio

Assistant Professor

Mayo Clinic

UNITED STATES

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James Davies

University of Oxford

UNITED KINGDOM

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Paul Moss

University of Birmingham

UNITED KINGDOM

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Ralf Küppers

Professor

Universität Duisburg-Essen

GERMANY

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Jianguo Zhuang

Honorary Senior Lecturer

University of Liverpool

UNITED KINGDOM

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Bin Qu

GERMANY

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King’s College London

UNITED KINGDOM

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Sarah Wordsworth

Professor

University of Oxford

UNITED KINGDOM

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Alan Ramsay

Research Interests

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Recent Grants

Articles (17)

Progressive T cell defects correlate with disease outcome in high-count monoclonal B-cell lymphocytosis

Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma

Interleukin-27 potentiates CD8+ T-cell-mediated antitumor immunity in chronic lymphocytic leukemia

Ibrutinib-based therapy reinvigorates CD8 T cells compared to chemoimmunotherapy: immune-monitoring from the E1912 trial

The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy

Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features

Distinct Chemokine Receptor Expression Profiles in De Novo DLBCL, Transformed Follicular Lymphoma, Richter’s Trans-Formed DLBCL and Germinal Center B-Cells

Activation and expansion of T-follicular helper cells in chronic lymphocytic leukemia nurselike cell co-cultures

Extracellular vesicle secretion by leukemia cells in vivo promotes CLL progression by hampering antitumor T-cell responses

Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity

Immunomodulatory Drugs for the Treatment of B Cell Malignancies

ImmunoCluster provides a computational framework for the nonspecialist to profile high-dimensional cytometry data

Targeting the tumor microenvironment in chronic lymphocytic leukemia

Understanding the Immune-Stroma Microenvironment in B Cell Malignancies for Effective Immunotherapy

A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice

Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1/PD-1 immunotherapy

T-Cell Dynamics in Chronic Lymphocytic Leukemia under Different Treatment Modalities

Collaborators (18)

Esteban Braggio

James Davies

Paul Moss

Ralf Küppers

Jianguo Zhuang

Bin Qu

Felix Bruno Kleine Borgmann

Martin Pichler

Elizabeth Phillips

Zeev Estrov

Andrea Pepper

Piers Patten

SUTAPA SINHA

James Allan

Samantha Knight

Professor Jonathan C Strefford

peter parker

Sarah Wordsworth

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