Albena Dinkova-Kostova

Academic, Professor (Teaching and Research) of Chemical Biology

University of Dundee

United Kingdom

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Albena Dinkova-Kostova is a Professor of Chemical Biology at the University of Dundee, UK. Her research focuses on the Nrf2 pathway and its implications in non-communicable diseases, oxidative stress, and the pharmacological regulation of health. Recent articles include studies on quinoline derivatives, genetic deletion effects in obesity, and the use of nutritional supplements for respiratory infections.

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2025

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2023

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2023

Collaborators (18)

Matthias Pawlowski

Universitätsklinikum Münster

GERMANY

Albena Dinkova-Kostova

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Articles (20)

Genetic Deletion of RHAMM Alleviates Hepatic Oxidative Stress, Reversing Thyroid Stimulating Hormone Elevation in Male Obese Mice

Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases

CD5L is a target of transcription factor Nrf2

Regulating Nrf2 activity: ubiquitin ligases and signaling molecules in redox homeostasis

Exploring nutritional supplement use for countering respiratory tract infections through an X (formerly Twitter)-based survey

NQO1 induction and radiation-based biodistribution study of a new quinoline derivative identified in a screen of 6,8-diiodoquinazolinone sulfonamide conjugates

Health position paper and redox perspectives – Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases

Activation of the Nrf2 pathway by sulforaphane improves hypoglycaemia-induced cognitive impairment in a rodent model of Type 1 diabetes

Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms

Correction

Advances and challenges in therapeutic targeting of NRF2

Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically-induced type 1 diabetes

Nrf2 depletion in the context of loss-of-function Keap1 leads to mitolysosome accumulation

Nrf2 regulates glucose uptake and metabolism in neurons and astrocytes

Omaveloxolone (SkyclarysTM) for patients with Friedreich's ataxia

The triterpenoid Nrf2 activator CDDO-Me decreases neutrophil senescence in a murine model of joint damage

NOX4-derived ROS are neuroprotective by balancing intracellular calcium stores

Nrf2 in TIME

Swietenine Alleviates Nonalcoholic Fatty Liver Disease in Diabetic Mice via Lipogenesis Inhibition and Antioxidant Mechanisms

Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic Stability

Collaborators (18)

Matthias Pawlowski

José Andrade

Michael Duchen

Ian Copple

Sharadha Dayalan Naidu

Jialin Feng

Michael Ashford

Laureano de la Vega

Ana I Rojo

Li Kang

Ulrik Pedersen-Bjergaard

Gabriela Rodrigues

Rory J. McCrimmon

Diogo Rodrigues Fernandes

Ana Rita Carlos

Miguel C. Seabra

Solveig Thorsteinsdottir

Jeffrey Huang

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