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Alena Pecinová

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Senior researcher

Institute of Physiology of the Czech Academy of Sciences

Czech Republic

Research Interests

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Professors in Biochemistry

Recent Grants

Grant: Close

Rearrangement of cellular metabolism triggered by impairment of oxidative phosphorylation

Open Date: 2021-01-01

Close Date: 2024-12-01

Grant: Close

Mitochondrial and nuclear DNA cross-talk and its impact on metabolic phenotype and innate immunity

Open Date: 2019-01-01

Close Date: 2022-06-01

Grant: Close

Targeting tumor cell proliferation by inhibitors of mitochondrial glycerophosphate dehydrogenase

Open Date: 2016-01-01

Close Date: 2018-12-01

Grant: Close

Targeting specific metabolic pathways to sensitize leukemic patients to L-asparaginase treatment

Open Date: 2015-05-01

Close Date: 2018-12-01

Articles (15)

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2026

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2023

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2023

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2023

Collaborators (18)

Michaela Tencerova

Group leader

Czech Academy of Sciences

CZECH REPUBLIC

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Irena Markova

Institute of Experimental Medicine

CZECH REPUBLIC

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Petr Pecina

Institute of Physiology of the Czech Academy of Sciences

CZECH REPUBLIC

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Institute of Biotechnology of the Czech Academy of Sciences

CZECH REPUBLIC

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Tomas Cajka

Institute of Physiology of the Czech Academy of Sciences

CZECH REPUBLIC

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Alena Pecinová

Research Interests

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Recent Grants

Articles (15)

Polyunsaturated fatty acid sequestration protects against mitochondrial dysfunction-induced ferroptosis.

The cytochrome c oxidase subunit COX6B1 is required for redox-sensitive early assembly and late stabilization of complex IV

Development of Cellular Energy Metabolism During Differentiation of Human iPSCs into Cortical Neurons

Bioenergetics of human spermatozoa in patients with testicular germ cell tumours

Cryopreserved PBMCs can be used for the analysis of mitochondrial respiration and serve as a diagnostic tool for mitochondrial diseases

Germline Jak2-R1063H mutation interferes with normal hematopoietic development and increases risk of thrombosis and leukemic transformation

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Sequestration of the polyunsaturated fatty acids protects the cells with oxidative phosphorylation deficiency from ferroptosis

Haplotype variability in mitochondrial rRNA predisposes to metabolic syndrome

Mitochondrial translation is the primary determinant of secondary mitochondrial complex I deficiencies

Czech Footprints in the Bioenergetics Research

Variability of Clinical Phenotypes Caused by Isolated Defects of Mitochondrial ATP Synthase

Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome

Omega-3 PUFAs prevent bone impairment and bone marrow adiposity in mouse model of obesity

Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy

Collaborators (18)

Michaela Tencerova

Irena Markova

Petr Pecina

Arzuv Čaryjeva

Marketa Hlavackova

Morten Svarer Hansen

Lukas Ded

Tomas Cajka

Erika Fernandez-Vizarra

Vishma Pratap Sur

Ivana Hermanova

Marketa Tesarova

Meritxell Alberich Jorda

Hana Hansikova

Hana Malinska

Jakub Otáhal

Jan Prochazka

Greet Kerckhofs

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