Alex Hughes

Assistant Professor

University of Pennsylvania

United States

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About

Dr. Alex Hughes is an Assistant Professor at the University of Pennsylvania, USA. His research focuses on kidney development, tissue engineering, and cell mechanobiology, as evidenced by his recent articles exploring topics such as kidney developmental trajectories, cell-laden composites, and engineered organoid production. Dr. Hughes employs innovative methodologies to investigate cell behavior and interactions within complex biological systems.

Articles (9)

Year:

2025

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2025

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2024

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2024

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2024

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2023

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2023

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2023

Year:

2020

Collaborators (1)

Jason A. Burdick

UNITED STATES

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Alex Hughes

Research Interests

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Articles (9)

Engineering kidney developmental trajectory using culture boundary conditions

Programmed Shape Transformations in Cell-laden Granular Composites

Measurement of adhesion and traction of cells at high yield reveals an energetic ratchet operating during nephron condensation

Highly parallel production of designer organoids by mosaic patterning of progenitors

Jamming of nephron-forming niches in the developing mouse kidney creates cyclical mechanical stresses

Independent control over cell patterning and adhesion on hydrogel substrates for tissue interface mechanobiology

The developing murine kidney actively negotiates geometric packing conflicts to avoid defects

Enhancing Single-Cell Western Blotting Sensitivity Using Diffusive Analyte Blotting and Antibody Conjugate Amplification

Guiding Cell Network Assembly using Shape‐Morphing Hydrogels

Collaborators (1)

Jason A. Burdick

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