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Alex Odermatt

Professor Dr

University of Basel

Switzerland

Research Interests

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Professors in Switzerland Professors in Biochemistry Biochemistry professors in Switzerland

About

Professor Dr. Alex Odermatt is a faculty member at the University of Basel in Switzerland. His research areas include pharmacology, drug interactions, and biochemical pathways related to various diseases. Recent publications highlight his work on drug candidates against helminth infections, insights into gastrointestinal toxicity, and advancements in understanding the interactome in breast cancer cells.

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Collaborators (26)

Nancy B. Hopf

Head of Sector - Exposure Science

SWITZERLAND

Alex Odermatt

Research Interests

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Articles (24)

Hormonal changes in professional printers exposed to phthalates suggesting potential disturbances of the hypothalamic–pituitary–gonadal axis

Alterations in glucocorticoid homeostasis following sleeve gastrectomy in male mice

What can we learn from the history of steroid metabolites and the ongoing identification of novel biologically active steroid metabolites?

Identification of xenobiotics interfering with 5α-reductase (SRD5A2) activity

Bisphenol TMC exhibits greater estrogenic activity than Bisphenol A and three other structural analogues exemplified by higher estrogen receptor α-mediated gene expression and breast cancer cell proliferation

Estimates of skin and blood concentrations of UV-filters: Insights from in vitro skin experiments

Synthesis and Multidisciplinary Preclinical Investigations of Ferrocenyl, Ruthenocenyl, and Benzyl Derivatives of Thiabendazole as New Drug Candidates against Soil-Transmitted Helminth Infections

Elucidation of B-cell specific drug immunogenicity liabilities via a novel ex vivo assay

A BioID-based approach uncovers the interactome of hexose-6-phosphate dehydrogenase in breast cancer cells and identifies anterior gradient protein 2 as an interacting partner

Discovery of non-steroidal aldo-keto reductase 1D1 inhibitors through automated screening and in vitro evaluation

Disruption of serotonin homeostasis in intestinal organoids provides insights into drug-induced gastrointestinal toxicity

Salt-sensitive hypertension in GR mutant rats is associated with altered plasma polyunsaturated fatty acid levels and aortic vascular reactivity

The long way from raw data to NAM-based information: Overview on data layers and processing steps

Identification of a human blood biomarker of pharmacological 11β‐hydroxysteroid dehydrogenase 1 inhibition

ER‐mitochondria contacts and cholesterol metabolism are disrupted by disease‐associated tau protein

Calcineurin regulates aldosterone production via dephosphorylation of NFATC4

A novel mouse model for an inducible gene modification in the renal thick ascending limb

Characterization of the interferences of systemic azole antifungal drugs with adrenal steroid biosynthesis using H295R cells and enzyme activity assays

Dissecting the mechanism of cytokine release induced by T-cell engagers highlights the contribution of neutrophils

Migration Modeling as a Valuable Tool for Exposure Assessment and Risk Characterization of Polyethylene Terephthalate Oligomers

Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: Protocol for a systematic evidence map

Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing

The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples

Androglobin, a chimeric mammalian globin, is required for male fertility

Collaborators (26)

Nancy B. Hopf

David Penton

Edith Hummler

Felix Beuschlein

Paolo Paganetti

Gilles Gasser

Jamal Bouitbir

Philip Marx-Stoelting

Sonja A. Wrobel

Anne Eckert

Serge Rudaz

Martin Smieško

Johannes Loffing

Andreas Papassotiropoulos

Loïc Sauteur

Anne-Christine Peyter

Darko Maric

Jürgen Götz

Roland H. Wenger

Sylvia Escher

Jan Hengstler

Amandine Grimm

Frank Welle

Salvatore Piscuoglio

Dieter Kressler

Linda Schenk

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