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Sylvia Escher

Division Director Safety Assessment and Toxicology; HEad of Department In Silico Toxicology

Fraunhofer-Gesellschaft

Germany

Research Interests

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Professors in Germany

Articles (19)

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2026

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2026

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2026

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2025

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2024

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2024

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2024

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2023

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2023

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2023

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2023

Collaborators (11)

Philip Marx-Stoelting

Scientific director/head of unit

Federal Institute for Risk Assessment (BfR)

GERMANY

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Robert Landsiedel

GERMANY

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Paul Jennings

University of Amsterdam

NETHERLANDS

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Rupert Kellner

Fraunhofer Institute for Translational Medicine and Pharmacology

GERMANY

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Mathieu Vinken

Vrije Universiteit Brussel

BELGIUM

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Vera Ritz

Head of Department

Federal Institute for Risk Assessment

GERMANY

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University of Amsterdam

NETHERLANDS

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James Rathman

Professor

Ohio State University

UNITED STATES

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Vera Rogiers

Vrije Universiteit Brussel

BELGIUM

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Britta A. Kühne

Bundesinstitut für Risikobewertung

GERMANY

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Alex Odermatt

Professor Dr

University of Basel

SWITZERLAND

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Sylvia Escher

Research Interests

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Articles (19)

Regulation of chemicals demands assessment of risks rather than identification of hazards only

The in vitro alkaline comet assay with liver models as a complementary tool for genotoxicity assessment of N-nitrosamines

Bridging the gap in chemical risk assessment: Leveraging metabolite similarity for enhanced read-across applications

Report on the European Partnership for Alternative Approaches to Animal Testing (EPAA) "New Approach Methodology (NAMs) User Forum", 30-31 October 2024, Helsinki, Finland

Animal-free Safety Assessment of Chemicals: Project Cluster for Implementation of Novel Strategies (ASPIS) definition of new approach methodologies

The long way from raw data to NAM-based information: Overview on data layers and processing steps

Report on the European Partnership for Alternative Approaches to Animal Testing (EPAA) “New Approach Methodologies (NAMs) User Forum Kick-Off Workshop”

A Unified Whole Lung PBK Model for Inhalational Uptake of Gases and Aerosols in Men

An Alternative Safety Profiling Algorithm (ASPA) to transform next generation risk assessment into a structured and transparent process

Estimation of bioavailable concentration of endogenously formed N-nitrosamines by physiologically based kinetic modelling

Quantitative Investigation of Nitrosamine Drug Substance-Related Impurities (NDSRIs) Under Artificial Gastric Conditions by Liquid Chromatography-Tandem Mass Spectrometry and Structure-Activity Relationship Analysis

Retrospective analysis of clinical laboratory parameters in Han Wistar rat controls

Protectiveness of NAM-based hazard assessment - which testing scope is required?

Read‐Across Application for Food or Feed Ingredients

Screening for emerging chemical risks in the food chain (SCREENER)

Substantiate a read-across hypothesis by using transcriptome data—A case study on volatile diketones

Update of the Cancer Potency Database (CPDB) to enable derivations of Thresholds of Toxicological Concern (TTC) for cancer potency

Exposure considerations in human safety assessment: Report from an EPAA Partners' Forum

Toward implementing virtual control groups in nonclinical safety studies

Collaborators (11)

Philip Marx-Stoelting

Robert Landsiedel

Paul Jennings

Rupert Kellner

Mathieu Vinken

Vera Ritz

giada carta

James Rathman

Vera Rogiers

Britta A. Kühne

Alex Odermatt

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