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Alex von Kriegsheim

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Group Leader

University of Edinburgh

United Kingdom

Research Interests

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Recent Grants

Grant: Open

Generation of a multivariate stratification model to predict Trametinib-sensitive low-grade serous ovarian cancer tumours

Open Date: 2023-09-01

Close Date: 2027-02-28

Grant: Close

Robotic workstation to enable multiplexing for single-cell proteomics

Open Date: 2023-07-01

Close Date: 2024-06-30

Grant: Close

Artificial Intelligence (AI)-driven Laser Microdissection (LMD) microscope for spatial 'omics

Open Date: 2023-07-01

Close Date: 2024-03-31

Grant: Close

Ultra-sensitive Mass spectrometry for Precision Medicine

Open Date: 2022-10-31

Close Date: 2023-03-30

Grant: Close

Modelling hyperplastic and hypertrophic adipose tissue growth in zebrafish

Open Date: 2022-10-01

Close Date: 2026-09-30

Articles (20)

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Collaborators (29)

Roopesh Krishnankutty

Assistant Professor of Biochemistry and Molecular Biology

Mayo Clinic Florida

UNITED STATES

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Timothy Budden

Lecturer

University of Liverpool

UNITED KINGDOM

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Roly Megaw

Clinical Lecturer

University of Edinburgh

UNITED KINGDOM

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Giacomo Maria Bacci

AOU Meyer

ITALY

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Anabel Martinez Lyons

University of Edinburgh

UNITED KINGDOM

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Ben O'Leary

Group Leader

Institute of Cancer Research

UNITED KINGDOM

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Stuart Aitken

Staff Scientist

University of Edinburgh

UNITED KINGDOM

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Jacob Anderson

Harvard University

UNITED STATES

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Ann Wheeler

Head of Advanced Microscopy Facility

University of Edinburgh

UNITED KINGDOM

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Gareth Inman

Director of Research Strategy

Cancer Research UK Beatson Institute

UNITED KINGDOM

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Christoph Knosalla

Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin

GERMANY

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Miao Gui

Principal investigator

Zhejiang University

CHINA

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Stefan Unger

Senior Clinical Lecturer

University of Edinburgh

UNITED KINGDOM

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Abdenour Soufi

Principle Investigator, Senior Lecturer

University of Edinburgh

UNITED KINGDOM

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Antonio José Rullán

University College London

UNITED KINGDOM

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Walter Kolch

Dublin City University

IRELAND

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Lan Nguyen

Laboratory Head (Group Leader)

MONASH UNIVERSITY

AUSTRALIA

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Edward Jarman

Lecturer

University of Leicester

UNITED KINGDOM

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Yanfeng Zhang

Assistant Professor

The University of Alabama

UNITED STATES

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Martin Lee

University of Edinburgh

UNITED KINGDOM

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Kevin Harrington

Head of Division of Radiotherapy and Imaging

Institute of Cancer Research

UNITED KINGDOM

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Abigail Moye

Institute of Molecular and Clinical Ophthalmology Basel

SWITZERLAND

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David Matallanas

Assistant professor

Dublin City University

IRELAND

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Cheng Zhang

University of Texas Southwestern Medical Center

UNITED STATES

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Jean‐Michel Rozet

FRANCE

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Thomas Muenzel

Chief in Cardiology/Professor

Johannes Gutenberg Universität Mainz

GERMANY

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Adam Byron

Lecturer

The University of Manchester

UNITED KINGDOM

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Bharath Anila Bhuvanendran Nair

Researcher

University of Southern Denmark

DENMARK

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Amelia Shoemark

Asthma Lung UK GSK Chair of Respiratory Research

University of Dundee

UNITED KINGDOM

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Alex von Kriegsheim

Research Interests

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Recent Grants

Articles (20)

Tissue-specific fibroblast lipid cues impose the rate of epithelial cancer invasion

Acute co-exposure to urban particulate matter and aircraft noise elicits lung-centered immune-redox proteomic remodeling in mice

Changes in metabolomic profile in dogs with hepatic encephalopathy secondary to congenital portosystemic shunt suggests mitochondrial homeostasis disturbances

UBB as an early-stage potential biomarker for breast cancer via modulation of the ubiquitination pathway

GSTP1, PRDX2 and NFE2L2: Potential Markers for Primary Stage Breast Cancer

SOX2 phosphorylation during mitosis limits genomic damage

Tumour sampling conditions perturb the metabolic landscape of clear cell renal cell carcinoma

Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules

FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer

Ciliary tip actin dynamics regulate photoreceptor outer segment integrity

Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma.

Integrative modeling and analysis of signaling crosstalk reveal molecular switches coordinating Yes-associated protein transcriptional activities

Role of inflammatory signaling pathways involving the CD40-CD40L-TRAF cascade in diabetes and hypertension-insights from animal and human studies.

The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation

Van Gogh-like 2 is essential for the architectural patterning of the mammalian biliary tree

Involvement of Kindlin-1 in cutaneous squamous cell carcinoma

Selective Hypoxia-Sensitive Oxomer Formation by FIH Prevents Binding of the NF-κB Inhibitor IκBβ to NF-κB Subunits

Carbon, nitrogen, and sulfur elemental and isotopic variations in mouse hair and bone collagen during short-term graded calorie restriction

Proteomic Mapping of the Interactome of KRAS Mutants Identifies New Features of RAS Signalling Networks and the Mechanism of Action of Sotorasib

Co-exposure to urban particulate matter and aircraft noise adversely impacts the cerebro-pulmonary-cardiovascular axis in mice

Collaborators (29)

Roopesh Krishnankutty

Timothy Budden

Roly Megaw

Giacomo Maria Bacci

Anabel Martinez Lyons

Ben O'Leary

Stuart Aitken

Jacob Anderson

Ann Wheeler

Gareth Inman

Christoph Knosalla

Miao Gui

Stefan Unger

Abdenour Soufi

Antonio José Rullán

Walter Kolch

Lan Nguyen

Edward Jarman

Yanfeng Zhang

Martin Lee

Kevin Harrington

Abigail Moye

David Matallanas

Cheng Zhang

Jean‐Michel Rozet

Thomas Muenzel

Adam Byron

Bharath Anila Bhuvanendran Nair

Amelia Shoemark

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