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Alexander Pasternak

Has grant

Assistant Professor

Amsterdam University Medical Centers

Netherlands

Research Interests

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Recent Grants

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Viral and host factors determining immunological failure despite virological success on antiretroviral therapy

Open Date: 2012-01-01

Close Date:

Grant: Close

HIV-1 reservoir and viral diversity in patients treated with ART during primary infection

Open Date: 2011-01-01

Close Date: 2016-01-01

Articles (16)

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2023

Collaborators (11)

Andreas Reuter

Head of Proteomics Core Facility

Paul-Ehrlich-Institut

GERMANY

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Christian Buchholz

Paul-Ehrlich-Institut

GERMANY

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Tetsuo Tsukamoto

Professor

Niigata University of Health and Welfare

JAPAN

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Paolo Maiuri

Associate Professor

Università degli Studi di Napoli Federico II

ITALY

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Jessica Hartmann

Senior Researcher and Regulatory Assessor

Paul-Ehrlich-Institut

GERMANY

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Anna Kula-Pacurar

Assistant Professor

Jagiellonian University

POLAND

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Neeltje A Kootstra

Principal Investigator

Amsterdam University Medical Centers

NETHERLANDS

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Elena Herrera Carrillo

Principal Investigator

Amsterdam UMC Locatie AMC

NETHERLANDS

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Marlous Grijsen

University of Oxford

UNITED KINGDOM

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Tokameh Mahmoudi

Erasmus University Medical Center

NETHERLANDS

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Carine Van Lint

Université libre de Bruxelles (ULB)

BELGIUM

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Alexander Pasternak

Research Interests

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Recent Grants

Articles (16)

Doubling dolutegravir dosage reduces the viral reservoir in ART-treated people with HIV.

HIV-specific CD8+ T-cell proliferative response 24 weeks after early antiretroviral therapy initiation is associated with the subsequent reduction in the viral reservoir

Early intervention, lasting impact: benefits of early antiretroviral therapy and implications for posttreatment control

Nuclear retention of unspliced HIV-1 RNA as a reversible post-transcriptional block in latency

Long-term effect of temporary ART initiated during primary HIV-1 infection on viral persistence

Inhibition of ALKBH5 demethylase of m6A pathway potentiates HIV-1 reactivation from latency

No associations between HIV reservoir and inflammation in long-term virally suppressed dolutegravir-based ART-treated individuals

Phenotyping Viral Reservoirs to Reveal HIV-1 Hiding Places

Soluble CD14 and IL-12p70 on early antiretroviral therapy predict HIV load setpoint after treatment interruption

Soluble markers of viral rebound and post-treatment HIV control

Persistent HIV-1 transcription during ART: Time to reassess its significance?

FcγRIIA-specific DARPins as novel tools in blood cell analysis and platelet aggregation.

Corrigendum: Editorial: The relevance of molecular mechanisms in HIV-1 latency and reactivation from latency (Frontiers in Cellular and Infection Microbiology, (2023), 13, (1190867), 10.3389/fcimb.2023.1190867)

Editorial: The relevance of molecular mechanisms in HIV-1 latency and reactivation from latency

‘Zombie’ proviruses in the spotlight: exploring the dark side of HIV persistence

HIV persistence: silence or resistance?

Collaborators (11)

Andreas Reuter

Christian Buchholz

Tetsuo Tsukamoto

Paolo Maiuri

Jessica Hartmann

Anna Kula-Pacurar

Neeltje A Kootstra

Elena Herrera Carrillo

Marlous Grijsen

Tokameh Mahmoudi

Carine Van Lint

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