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Alexander Scheffold

Head of Department

Technische Universität Berlin

Germany

Research Interests

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Articles (20)

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2026

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Collaborators (24)

Antigoni Triantafyllopoulou

Prof. Dr.

Charité - Universitätsmedizin Berlin

GERMANY

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Julius Hoffmann

Charité - Universitätsmedizin Berlin

GERMANY

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Jan Rupp

University Hospital Schleswig-Holstein

GERMANY

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Dieter Kabelitz

Professor emertus

University Hospital Schleswig-Holstein

GERMANY

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Julia K. Polansky

Prof, Group leader

Charité - Universitätsmedizin Berlin

GERMANY

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Matthew Blango

Junior Group Leader

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie eV Hans-Knöll-Institut

GERMANY

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Mir-Farzin Mashreghi

Group Leader

Deutsches Rheuma-Forschungszentrum Berlin

GERMANY

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Klarissa Hanja Stürner

Christian-Albrechts-Universität zu Kiel

GERMANY

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Maria Buthut

Charite Universitatsmedizin Berlin Klinik für Neurologie mit Experimenteller Neurologie

GERMANY

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Wei Shi

Professor

MONASH UNIVERSITY

AUSTRALIA

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Ralf Ludwig

University Hospital Schleswig-Holstein

GERMANY

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Andreas Hutloff

Professor

University Hospital Schleswig-Holstein

GERMANY

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Kristina Koop

Junior research group leader

Friedrich-Alexander Universität Erlangen-Nürnberg

GERMANY

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Christian Peters

Head of Flow Cytometry Core Facility

University Hospital Schleswig-Holstein

GERMANY

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Rolf Backofen

Full Professor

GERMANY

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Jakob Kreye

GERMANY

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Benedikt Obermayer

Berlin Institute of Health at Charité - Universitätsmedizin Berlin

GERMANY

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Franz-Josef Müller

Professor for Neuropsychiatry

University Hospital Schleswig-Holstein

GERMANY

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Ahmed N. Hegazy

Lichtenberg-Professor für Translationale Gastroenterologie

Charite Universitätsmedizin

GERMANY

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Margitta Worm

GERMANY

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Frank Ebel

Head of Mycology Group

Ludwig-Maximilians-Universität München

GERMANY

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Sarah Temmam

Head of the Pole for Genotyping of Pathogens (PGP)

Institut Pasteur

FRANCE

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Jochen G. Mainz

Head of Department Pediatric Pulmonology / CF Center

GERMANY

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Linda Odenthal-Hesse

Research Group Leader

Max Planck Institute for Evolutionary Biology

GERMANY

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Alexander Scheffold

Research Interests

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Articles (20)

Depletion of regulatory T cells breaks self-tolerance and induces epidermolysis bullosa acquisita in resistant C57BL/6J mice

Blinatumomab-driven T-cell activation in αβ and γδ T-cell subsets: insights from <i>in vitro</i> assays

Frequency of synaptic antigen-specific CD4&lt;sup&gt;+&lt;/sup&gt; T cells in dementia is age-dependent but not correlated with cognitive impairment.

Detection and Characterisation of Wasp Venom-Specific T Cells Using the ARTE Method in Allergic Patients.

Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4+ T Cells as Predictors for Response to Integrin α4β7-Blocking Therapy in Inflammatory Bowel Disease.

Butyrophilin 3A/2A1-independent activation of human Vγ9Vδ2 γδ T cells by bacteria

A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation

Integrin αVβ6: Autoantigen and Driver of Epithelial Remodeling in Colon and Bile Ducts in Primary Sclerosing Cholangitis and Inflammatory Bowel Disease

The role of allergen-specific regulatory T cells in the control of allergic disease

Autoantigen-specific CD4+T cells acquire an exhausted phenotype and persist in patients with autoimmune diseases

Engineering Therapeutic Regulatory T Cells to Overexpress G Protein-Coupled Receptor 15 Improves Functional Fitness for In Vivo Gut Homing

TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice

Author Correction: c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis (Nature Immunology, (2019), 20, 4, (471-481), 10.1038/s41590-019-0316-2)

Spatial Single Cell Profiling Using Imaging Mass Cytometry: Inflammatory Versus Penetrating Crohn's Disease

Autoantigen-specific CD4+ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases.

Advancing evolutionary medicine in Northern Germany

Preschool-age children maintain a distinct memory CD4 + T cell and memory B cell response after SARS-CoV-2 infection

Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn’s disease

Proliferative activity of antigen-specific CD154+ T cells against bacterial and fungal respiratory pathogens in cystic fibrosis decreases after initiation of highly effective CFTR modulator therapy

Antigen specificity and cross-reactivity drive functionally diverse anti–Aspergillus fumigatus T cell responses in cystic fibrosis

Collaborators (24)

Antigoni Triantafyllopoulou

Julius Hoffmann

Jan Rupp

Dieter Kabelitz

Julia K. Polansky

Matthew Blango

Mir-Farzin Mashreghi

Klarissa Hanja Stürner

Maria Buthut

Wei Shi

Ralf Ludwig

Andreas Hutloff

Kristina Koop

Christian Peters

Rolf Backofen

Jakob Kreye

Benedikt Obermayer

Franz-Josef Müller

Ahmed N. Hegazy

Margitta Worm

Frank Ebel

Sarah Temmam

Jochen G. Mainz

Linda Odenthal-Hesse

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Frequency of synaptic antigen-specific CD4<sup>+</sup> T cells in dementia is age-dependent but not correlated with cognitive impairment.