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Alexandre Kauskot

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Chercheur/Researcher

INSERM

France

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Professors in France Professors in Cell Biology Cell Biology professors in France

Recent Grants

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ACTOMIC

Open Date: 2022-01-01

Close Date: 2026-01-01

Grant: Close

MACROIT

Open Date: 2022-01-01

Close Date: 2025-01-01

Grant: Close

Thrombopénie/thrombopathie par désialylation des plaquettes dans la maladie de Willebrand de type 2B.

Open Date: 2017-01-01

Close Date: 2020-01-01

Grant: Close

TRIMEP

Open Date: 2017-01-01

Close Date: 2020-01-01

Grant: Close

Rol van PEAR1 in bloedplaatjesvorming en functie.

Open Date: 2011-01-01

Close Date: 2011-12-31

Articles (14)

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2025

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2025

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2023

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2023

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2023

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2023

Year:

2023

Collaborators (19)

francesco baschieri

Assistant professor

Medical University of Innsbruck

AUSTRIA

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Quentin RILLER

Imagine Institute for Genetic Diseases

FRANCE

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Carmelo Bernabeu

Research Professor

SPAIN

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samuela pasquali

Professor

Université Paris-Saclay

FRANCE

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Frédéric ADAM

INSERM UMR 1236

FRANCE

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Cecile Denis

INSERM

FRANCE

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Elisa Rossi

Full Professor

Université Paris Descartes

FRANCE

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Luca Jovine

Professor of Structural Biology

Karolinska Institutet

SWEDEN

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Nathalie Janel

Université Paris Cité

FRANCE

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Régis Bobe

INSERM

FRANCE

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Gautier Moroy

Université Paris-Saclay

FRANCE

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Arnaud Bruneel

Associate professor and senior clinical biochemist (MCU-PH)

INSERM

FRANCE

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Christian Andrea DI BUDUO

Associate Professor

University of Pavia

ITALY

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Sofia Ramström

Ass. prof

Örebro university

SWEDEN

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M. Cristina Vega

Head of Department

Centro de Investigaciones Biológicas Margarita Salas

SPAIN

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Fernando Sepulveda

Lab Director

Imagine Institute for Genetic Diseases

FRANCE

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charline miot

Assistant Professor in Immunology

Université d'Angers

FRANCE

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Alain Stépanian

Professor

University of Montpellier

FRANCE

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ILEANA ANTONY-DEBRE

INSERM

FRANCE

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Alexandre Kauskot

Research Interests

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Recent Grants

Articles (14)

Consensus protocol for platelet desialylation (β-galactose exposure) quantification using lectins by flow cytometry: communication from the ISTH SSC Subcommittee on Platelet Physiology.

F-actin disassembly by the oxidoreductase MICAL1 promotes mechano-dependent VWF-GPIbα interaction in platelets

Thrombin cleaves membrane-bound endoglin potentially contributing to the heterogeneity of circulating endoglin in preeclampsia

Unveiling platelet aging with progressive β-galactose exposure as a signature of platelet senescence in humans and mice

Increased RhoA pathway activation downstream of αIIbβ3/SRC contributes to heterozygous Bernard Soulier syndrome

vWF/GPIb mechano-dependent interactions require F-actin disassembly by the oxidoreductase MICAL1

Somatic RAP1B gain-of-function variant underlies isolated thrombocytopenia and immunodeficiency

Deregulation of the p19/CDK4/CDK6 axis in Jak2<sup>V617F</sup> megakaryocytes accelerates the development of myelofibrosis.

MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation

DOCK11 deficiency in patients with X-linked actinopathy and autoimmunity

ADP receptor P2Y12 is the capstone of the cross-talk between Ca2+ mobilization pathways dependent on Ca2+ ATPases sarcoplasmic/endoplasmic reticulum type 3 and type 2b in platelets

Over‐expression of <scp>Dyrk1A</scp> affects bleeding by modulating plasma fibronectin and fibrinogen level in mice

Soluble endoglin reduces thrombus formation and platelet aggregation via interaction with αIIbβ3 integrin

OC 58.1 Circulating Endoglin Decreases Platelet Aggregation and Thrombus Formation through Interaction with the αIIbβ3 Integrin

Collaborators (19)

francesco baschieri

Quentin RILLER

Carmelo Bernabeu

samuela pasquali

Frédéric ADAM

Cecile Denis

Elisa Rossi

Luca Jovine

Nathalie Janel

Régis Bobe

Gautier Moroy

Arnaud Bruneel

Christian Andrea DI BUDUO

Sofia Ramström

M. Cristina Vega

Fernando Sepulveda

charline miot

Alain Stépanian

ILEANA ANTONY-DEBRE

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