Ali Mobasheri

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Professor of Musculoskeletal Biology

University of Oulu

Finland

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Ali Mobasheri is a Professor of Musculoskeletal Biology at the University of Oulu, Finland. His research focuses on the pathophysiology and treatment of osteoarthritis, with recent publications addressing imaging strategies for clinical trials, inflammatory endotypes, and advancements in diagnostics and therapeutics related to extracellular matrix. He has also explored non-invasive models for knee joint injuries, the role of obesity in osteoarthritis, and innovative platforms for studying cartilage dynamics.

Recent Grants

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CHONDRION - Chondrocyte ion channel function and regulation in health and disease

Open Date: 2014-10-01

Close Date: 2016-09-01

Grant: Close

Novel Diagnostics and Biomarkers for Early Identification of Chronic Inflammatory Joint Diseases

Open Date: 2012-10-01

Close Date: 2017-09-01

Grant: Close

Metabolic activity and viability of chondrocytes in cryopreserved human osteochondral allografts

Open Date: 2007-09-01

Close Date: 2011-02-28

Grant: Close

Metabolic activity and viability of chondrocytes in cryopreserved human osteochondral allografts

Open Date: 2007-09-01

Close Date: 2011-02-28

Ali Mobasheri

Research Interests

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About

Recent Grants

Articles (20)

Advances in Extracellular Matrix-Associated Diagnostics and Therapeutics

Multifaceted imaging strategies for clinical trials of knee osteoarthritis—a tightly interlinked value and precision chain

The inflammatory endotype in osteoarthritis: Reflections from the 2024 OARSI clinical trials symposium (CTS) with a special emphasis on feasibility for clinical development

Comment on “Surgical restabilization reduces the progression of post-traumatic osteoarthritis initiated by ACL rupture in mice” by Lin et al. (2024), and recommendations for non-invasive knee joint injury models

Comment on “Effectiveness and safety of intra-articular interventions for knee and hip osteoarthritis based on large randomized trials: A systematic review and network meta-analysis (Pereira et al., 2025)”

TissueGene-C induces anti-inflammatory activity and M2 macrophage polarization via activation of prostaglandin E2 signaling

Development of a Microphysiological Cartilage‐on‐Chip Platform for Dynamic Biomechanical Stimulation of Three‐Dimensional Encapsulated Chondrocytes in Agarose Hydrogels

Obesity-induced fibrosis in osteoarthritis: Pathogenesis, consequences and novel therapeutic opportunities

Correction: Giunta et al. Ameliorative Effects of PACAP against Cartilage Degeneration. Morphological, Immunohistochemical and Biochemical Evidence from in Vivo and in Vitro Models of Rat Osteoarthritis. Int. J. Mol. Sci. 2015, 16, 5922–5944

Targeting the TRPV1 pain pathway in osteoarthritis of the knee

Low‐dose ketamine improves animals' locomotor activity and decreases brain oxidative stress and inflammation in ammonia‐induced neurotoxicity

Ion channels involved in inflammation and pain in osteoarthritis and related musculoskeletal disorders

The Effect of CaV1.2 Inhibitor Nifedipine on Chondrogenic Differentiation of Human Bone Marrow or Menstrual Blood-Derived Mesenchymal Stem Cells and Chondrocytes

Predicting osteoarthritis onset and progression with 3D texture analysis of cartilage MRI DESS: 6‐Year data from osteoarthritis initiative

“Self-Healing”: A Novel and Integrated Multimodal Concept for the Management of Musculoskeletal Pain

Minimally Invasive Cell-Based Therapy for Symptomatic Bone Marrow Lesions of the Knee: A Prospective Clinical Study at 1 Year

Osteoarthritis endotype discovery via clustering of biochemical marker data

Intra-Articular Injection of Platelet-Rich Plasma Is More Effective than Hyaluronic Acid or Steroid Injection in the Treatment of Mild to Moderate Knee Osteoarthritis: A Prospective, Randomized, Triple-Parallel Clinical Trial

Magneto-Immunoassay for the Detection and Quantification of Human Growth Hormone

A new immunometabolic perspective of intervertebral disc degeneration

Collaborators (13)

Yves Henrotin

André Struglics

Scott Friedman

Paresh Thakker

Jan Zabrzynski

Andrea Heinz

Roland Takács

Jesus Pino

Federica Genovese

Alexander Eckersley

Csaba Matta

Richard Loeser

Miika Nieminen

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