Alistair JP Brown

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Professor & Co-Director

University of Exeter

United Kingdom

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About

Alistair JP Brown is a Professor and Co-Director at the University of Exeter, UK. His research primarily focuses on fungal pathobiology, examining interactions between fungal pathogens and host immune responses. Recent publications have explored topics such as metabolic modeling for Pneumocystis growth, the effects of short-chain fatty acids on gut health, and CRISPR-based tools for genetic manipulation in pathogenic fungi.

Recent Grants

Grant: Close

Mechanisms linking phosphate acquisition, stress resistance and virulence in the fungal pathogen, Candida albicans

Open Date: 2017-10-01

Close Date: 2020-09-01

Grant: Close

Zeiss LSM 880 confocal microscope with Airyscan detector for super-resolution imaging at the University of Aberdeen

Open Date: 2017-09-01

Close Date: 2018-09-01

Grant: Close

Impact of fungal adaptation upon host recognition and pathogenesis

Open Date: 2016-01-01

Close Date: 2021-01-01

Grant: Close

Quantitative Proteomics Equipment for the Aberdeen Proteomics Facility.

Open Date: 2014-11-01

Close Date: 2015-10-31

Grant: Close

Wellcome Strategic Award for Medical Mycology and Fungal Immunology

Open Date: 2012-05-08

Close Date: 2020-04-30

Articles (17)

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2020

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2020

Collaborators (16)

Alessandra da Silva Dantas

Lecturer

Newcastle University

UNITED KINGDOM

Alistair JP Brown

Research Interests

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About

Recent Grants

Articles (17)

Effects of Short-Chain Fatty Acid Combinations Relevant to the Healthy and Dysbiotic Gut upon Candida albicans

Candida auris undergoes adhesin-dependent and -independent cellular aggregation

The pathobiology of human fungal infections

Fungal pathogens and symbionts: Living off the fat of the land

Metabolic modelling as a powerful tool to identify critical components of Pneumocystis growth medium

Hyphal swelling induced in the phagosome of macrophages

Slicing through the challenge of maintaining Pneumocystis in the laboratory

CRISPR-based tools for targeted genetic manipulation in pathogenic Sporothrix species

Fungal spore swelling and germination are restricted by the macrophage phagolysosome

Heightened Efficacy of Anidulafungin When Used in Combination with Manogepix or 5-Flucytosine against Candida auris In Vitro

Analysis of Pneumocystis Transcription Factor Evolution and Implications for Biology and Lifestyle

Fungal resilience and host–pathogen interactions: Future perspectives and opportunities

Human gut bifidobacteria inhibit the growth of the opportunistic fungal pathogen Candida albicans

Understanding the Role of Nitronate Monooxygenases in Virulence of the Human Fungal Pathogen Aspergillus fumigatus

Transcriptomic and proteomic profiling revealed reprogramming of carbon metabolism in acetate-grown human pathogen Candida glabrata

Epitope Shaving Promotes Fungal Immune Evasion

The environmental stress sensitivities of pathogenic Candida species, including Candida auris, and implications for their spread in the hospital setting

Collaborators (16)

Alessandra da Silva Dantas

Olga A. Nev

Peter Cook

Neil Gow

Joseph Heitman

Marco Coelho

Alexander Lorenz

Alexandra Brand

Roberta Peres da Silva

Rhys Farrer

Romain De Oliveira

Alan Walker

judith bain

Sylvia Duncan

Steven Bates

Thomas Harrison

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