Allan Haldane

Research Assiciate Professor

Temple University

United States

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Allan Haldane is a Research Associate Professor at Temple University, United States. His research primarily focuses on polycystin-1 signaling, the evolutionary dynamics of kinases, HIV-1 integrase resistance, and probabilistic protein sequence modeling. His recent publications explore various aspects of protein function and resistance mechanisms in viral systems.

Articles (8)

Year:

2024

Year:

2024

Year:

2024

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2023

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Collaborators (2)

Yinglong Miao

Assistant Professor

University of Kansas

UNITED STATES

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Vincenzo Carnevale

Research Professor

Temple University

UNITED STATES

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Allan Haldane

Research Interests

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Articles (8)

Evolutionary sequence and structural basis for the distinct conformational landscapes of Tyr and Ser/Thr kinases

Activation of polycystin-1 signaling by binding of stalk-derived peptide agonists

Activation of polycystin-1 signaling by binding of stalk-derived peptide agonists

Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants

Evolutionary divergence in the conformational landscapes of tyrosine vs serine/threonine kinases

Limits to detecting epistasis in the fitness landscape of HIV

The generative capacity of probabilistic protein sequence models

Mi3-GPU: MCMC-based inverse Ising inference on GPUs for protein covariation analysis

Collaborators (2)

Yinglong Miao

Vincenzo Carnevale

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