Alyson Fiorillo

Assistant Professor

Children's National Health System

United States

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About

Alyson Fiorillo is an Assistant Professor at the Children's National Health System in the United States. Her research focuses on muscular dystrophies, particularly the molecular and therapeutic aspects of dystrophin restoration and microRNA regulation. Recent articles highlight her work on protein restoration therapies, the effects of glucocorticoid receptors in dystrophic muscle, and the identification of biomarkers for various muscular conditions.

Articles (10)

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2024

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2024

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2023

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2023

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2021

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2021

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2020

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2020

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Denali Therapeutics

UNITED STATES

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Alyson Fiorillo

Research Interests

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Articles (10)

Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping

The glucocorticoid receptor acts locally to protect dystrophic muscle and heart during disease

The X‐linked Becker muscular dystrophy (bmx) mouse models Becker muscular dystrophy via deletion of murine dystrophin exons 45–47

Vamorolone improves Becker muscular dystrophy and increases dystrophin protein in bmx model mice.

Effects of Chronic, Maximal Phosphorodiamidate Morpholino Oligomer (PMO) Dosing on Muscle Function and Dystrophin Restoration in a Mouse Model of Duchenne Muscular Dystrophy

Interrogation of Dystrophin and Dystroglycan Complex Protein Turnover After Exon Skipping Therapy

Multi-Omics Identifies Circulating miRNA and Protein Biomarkers for Facioscapulohumeral Dystrophy

Muscle Weakness in Myositis: MicroRNA‐Mediated Dystrophin Reduction in a Myositis Mouse Model and Human Muscle Biopsies

Estrogen Receptor, Inflammatory, and FOXO Transcription Factors Regulate Expression of Myasthenia Gravis-Associated Circulating microRNAs

Serum miRNAs Are Pharmacodynamic Biomarkers Associated With Therapeutic Response in Pediatric Inflammatory Bowel Disease.

Collaborators (5)

Christopher Heier

Davi Mázala

Eric Hoffman

Katie Edwards

Breanne Newell-Stamper

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