Amin Rostami-Hodjegan

The Director & Professor of Systems Pharmacology

The University of Manchester

United Kingdom

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Articles (10)

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Collaborators (4)

Brahim Achour

Assistant Professor

University of Rhode Island

UNITED STATES

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Aleksandra Galetin

UNITED KINGDOM

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Zubida M. Al-Majdoub

The University of Manchester

UNITED KINGDOM

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Daniel Scotcher

The University of Manchester

UNITED KINGDOM

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Amin Rostami-Hodjegan

Research Interests

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Articles (10)

Development of 4‐Pyridoxic Acid PBPK Model to Support Biomarker‐Informed Evaluation of OAT1/3 Inhibition and Effect of Chronic Kidney Disease

In‐depth analysis of patterns in selection of different physiologically‐based pharmacokinetic modeling tools: Part II — Assessment of model reusability and comparison between open and non‐open source‐code software

Linking in vitro–in vivo extrapolations with physiologically based modeling to inform drug and formulation development

In‐depth analysis of patterns in selection of different physiologically based pharmacokinetic modeling tools: Part I – Applications and rationale behind the use of open source‐code software

Delineating gene–environment effects using virtual twins of patients treated with clozapine

Quantitative Assessment of the Impact of Crohn's Disease on Protein Abundance of Human Intestinal Drug-Metabolising Enzymes and Transporters

Effect of chronic kidney disease on the renal secretion via organic anion transporters (OAT)1/3: Implications for PBPK modelling and dose adjustment

Is Liquid Biopsy Only Restricted to Diagnostics or Can it Go Beyond the Confines of Genotyping and Phenotyping for Quantitative Pharmacology?

Altered Bioavailability and Pharmacokinetics in Crohn’s Disease: Capturing Systems Parameters for PBPK to Assist with Predicting the Fate of Orally Administered Drugs

Quality Assurance of PBPK Modeling Platforms and Guidance on Building, Evaluating, Verifying and Applying PBPK Models Prudently under the Umbrella of Qualification: Why, When, What, How and By Whom?

Collaborators (4)

Brahim Achour

Aleksandra Galetin

Zubida M. Al-Majdoub

Daniel Scotcher

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