Daniel Scotcher

The University of Manchester

United Kingdom

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Articles (10)

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

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2020

Year:

2020

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2020

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2020

Year:

2020

Collaborators (4)

Brahim Achour

Assistant Professor

University of Rhode Island

UNITED STATES

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Kayode Ogungbenro

Lecturer

The University of Manchester

UNITED KINGDOM

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Zubida M. Al-Majdoub

The University of Manchester

UNITED KINGDOM

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Amin Rostami-Hodjegan

The Director & Professor of Systems Pharmacology

The University of Manchester

UNITED KINGDOM

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Daniel Scotcher

Research Interests

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Articles (10)

Coproporphyrin I as an endogenous biomarker to detect reduced OATP1B activity and shift in elimination route in chronic kidney disease

Effect of chronic kidney disease on the renal secretion via organic anion transporters (OAT)1/3: Implications for PBPK modelling and dose adjustment

Quantitative Proteomic Map of Enzymes and Transporters in the Human Kidney: Stepping Closer to Mechanistic Kidney Models to Define Local Kinetics

Hepatic Scaling Factors for In Vitro-In Vivo Extrapolation (IVIVE) of Metabolic Drug Clearance in Patients with Colorectal Cancer with Liver Metastasis

Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug–Drug Interactions

Mass Spectrometry‐Based Abundance Atlas of ABC Transporters in Human Liver, Gut, Kidney, Brain, and Skin

Physiologically-based Pharmacokinetic Modelling of Creatinine-drug Interactions in the Chronic Kidney Disease Population

Scaling Factors for Clearance in Adult Liver Cirrhosis

A novel physiologically based model of creatinine renal disposition to integrate current knowledge of systems parameters and clinical observations

Mechanistic models as framework for understanding biomarker disposition

Collaborators (4)

Brahim Achour

Kayode Ogungbenro

Zubida M. Al-Majdoub

Amin Rostami-Hodjegan

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