Andreas Plückthun

University of Zurich

Switzerland

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Articles (21)

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2025

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2022

Collaborators (16)

Ohad Medalia

SWITZERLAND

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Wim Versées

Vrije Universiteit Brussel

BELGIUM

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Sheena Nichole Smith

Head of Program Management

SWITZERLAND

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Christian Galicia Diaz Santana

Vrije Universiteit Brussel

BELGIUM

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Christoph Klenk

Professor

University of Giessen

GERMANY

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Rainer Riedl

Professor of Organic and Medicinal Chemistry

Zürcher Hochschule für Angewandte Wissenschaften

SWITZERLAND

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Jason Holland

Associate Professor - Chair of Medicinal Radiochemistry

University of Zurich

SWITZERLAND

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Ryo Tachibana

University of Tokyo

JAPAN

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Patrick Ernst

Head Faculty Affairs

University of Zurich

SWITZERLAND

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laurent terradot

CNRS

FRANCE

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Anna Hine

Professor, 0.8 FTE

Aston University

UNITED KINGDOM

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Karin J. Metzner

University of Zurich

SWITZERLAND

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Katarzyna Justyna

Assistant Professor at the Institute of Organic Chemistry

Lodz University of Technology

POLAND

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Mark D. Distefano

UNITED STATES

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Harri Härmä

University of Turku

FINLAND

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Jose Maria Carazo Garcia

Full Professor

Centro Nacional de Biotecnología

SPAIN

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Andreas Plückthun

Research Interests

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Articles (21)

· Structural analysis of HER2-trastuzumab complex reveals receptor conformational adaptation

Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma

Genome-replicating HC-AdV – a novel high-capacity adenoviral vector class featuring enhanced in situ payload expression

Design of Antigen-Targeting Fluorogenic Probes Utilizing Intramolecular Addition Reaction of Protein-Dye Hybrids

Dendritic cell targeting in lymph nodes with modular adapters boosts HAdV5 and HC-HAdV5 tumor vaccination by co-secretion of IL-2v and IL-21

Broadening the Utility of Farnesyltransferase-Catalyzed Protein Labeling Using Norbornene–Tetrazine Click Chemistry

A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2

Modular binder technology by NGS-aided, high-resolution selection in yeast of designed armadillo modules

Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96

Designed Ankyrin Repeat Proteins as Actin Labels of Distinct Cytoskeletal Structures in Living Cells

Targeted shock-and-kill HIV-1 gene therapy approach combining CRISPR activation, suicide gene tBid and retargeted adenovirus delivery

Designed ankyrin repeat proteins for detecting prostate-specific antigen expression in vivo

Nuclear myosin VI maintains replication fork stability

Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system

CRISPR-clear imaging of melanin-rich B16-derived solid tumors

A Vaccinia-based system for directed evolution of GPCRs in mammalian cells

Improved Repeat Protein Stability by Combined Consensus and Computational Protein Design

Sortase-Mediated Site-Specific Conjugation and 89Zr-Radiolabeling of Designed Ankyrin Repeat Proteins for PET

Modular Adapters Utilizing Binders of Different Molecular Types Expand Cell-Targeting Options for Adenovirus Gene Delivery

International nonproprietary names for monoclonal antibodies: an evolving nomenclature system

Structure of a hydrophobic leucinostatin derivative determined by host lattice display

Collaborators (16)

Ohad Medalia

Wim Versées

Sheena Nichole Smith

Christian Galicia Diaz Santana

Christoph Klenk

Rainer Riedl

Jason Holland

Ryo Tachibana

Patrick Ernst

laurent terradot

Anna Hine

Karin J. Metzner

Katarzyna Justyna

Mark D. Distefano

Harri Härmä

Jose Maria Carazo Garcia

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