Mark D. Distefano

United States

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Articles (17)

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2025

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2025

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (12)

Walter Schmidt

University of Georgia

UNITED STATES

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William C. K. Pomerantz

University of Minnesota

UNITED STATES

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James Hougland

Professor

Syracuse University

UNITED STATES

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Edgar A. Arriaga

University of Minnesota

UNITED STATES

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Homme W. Hellinga

Duke University Medical Center

UNITED STATES

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Carston R. Wagner

University of Minnesota

UNITED STATES

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Katarzyna M. Błażewska

Associate Professor

Lodz University of Technology

POLAND

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Yuk Sham

University of Minnesota

UNITED STATES

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Andreas Plückthun

University of Zurich

SWITZERLAND

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Jakub Bělíček

Univerzita Palackého v Olomouci

CZECH REPUBLIC

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Ling Li

UNITED STATES

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Katarzyna Justyna

Assistant Professor at the Institute of Organic Chemistry

Lodz University of Technology

POLAND

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Mark D. Distefano

Research Interests

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Articles (17)

Engineering protein prenylation: an emerging tool for selective protein modification

In Vivo Metabolic Labeling with an Isoprenoid Probe Reveals APOE Allele-Specific Differences in the Prenylome

Broadening the Utility of Farnesyltransferase-Catalyzed Protein Labeling Using Norbornene–Tetrazine Click Chemistry

Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase

Multivalent Fluorinated Nanorings for On-Cell 19F NMR

Targeted Drug Delivery by MMAE Farnesyl-Bioconjugated Multivalent Chemically Self-Assembled Nanorings Induces Potent Receptor-Dependent Immunogenic Cell Death

GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS

Thinking outside the CaaX-box: an unusual reversible prenylation on ALDH9A1

Orthogonal Enzyme–Substrate Design Strategy for Discovery of Human Protein Palmitoyltransferase Substrates

Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation

Combining Isoprenoid Probes with Antibody Markers for Mass Cytometric Analysis of Prenylation in Single Cells

Engineering Biomimetic Trogocytosis with Farnesylated Chemically Self-Assembled Nanorings

Manipulating Cell Fates with Protein Conjugates

Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase

In Vivo Prenylomic Profiling in the Brain of a Transgenic Mouse Model of Alzheimer’s Disease Reveals Increased Prenylation of a Key Set of Proteins

Enzymatic Construction of DARPin-Based Targeted Delivery Systems Using Protein Farnesyltransferase and a Capture and Release Strategy

MALDI-MS Analysis of Peptide Libraries Expands the Scope of Substrates for Farnesyltransferase

Collaborators (12)

Walter Schmidt

William C. K. Pomerantz

James Hougland

Edgar A. Arriaga

Homme W. Hellinga

Carston R. Wagner

Katarzyna M. Błażewska

Yuk Sham

Andreas Plückthun

Jakub Bělíček

Ling Li

Katarzyna Justyna

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