Andrew Leidal

Assistant Professor

University of Calgary

Canada

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About

Dr. Andrew Leidal is an Assistant Professor at the University of Calgary, Canada. His research primarily focuses on autophagy and its implications in cancer metastasis and neurodegenerative diseases. Recent publications include studies on autophagic processes in breast cancer and the roles of autophagy-related proteins in extracellular vesicle biogenesis. Dr. Leidal's work contributes significantly to understanding cellular mechanisms underlying disease progression.

Articles (11)

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2025

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2022

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2022

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2021

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2021

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2021

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2020

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2020

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2020

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University of California, San Francisco

UNITED STATES

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Andrew Leidal

Research Interests

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About

Articles (11)

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH

Secretory autophagy maintains proteostasis upon lysosome inhibition

Secretory autophagy during lysosome inhibition (SALI)

GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network.

Emerging roles for the autophagy machinery in extracellular vesicle biogenesis and secretion

Beyond Autophagy: The Expanding Roles of ATG8 Proteins.

Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.

Ribosome profiling reveals a functional role for autophagy in mRNA translational control.

LC3-dependent extracellular vesicle loading and secretion (LDELS).

Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression.

Unraveling the mechanisms that specify molecules for secretion in extracellular vesicles.

Collaborators (6)

Arun Wiita

Jeroen Roose

Juliet Goldsmith

Torsten Wittmann

Jayanta Debnath

Eric Huang

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