Jeroen Roose

Professor & Vice Chair

UCSF Medical Center

United States

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Dr. Jeroen Roose is a Professor and Vice Chair at UCSF Medical Center in the United States. His research focuses on hematopoiesis, cancer metastasis, and immune cell signaling, as evidenced by his recent articles on single-cell proteomics and the roles of various pathways in disease progression. His work also explores the implications of SARS-CoV-2 infection on cellular mechanisms and the architecture of human brain metastases.

Articles (13)

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2025

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2025

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2024

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2023

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2022

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2021

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2021

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2021

Collaborators (6)

Irina Nazarenko

Head of the Exosome and Tumor Biology group

University Medical Center Freiburg

GERMANY

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Abbas Doosti

University of Michigan Medical School

UNITED STATES

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Yvonne Vercoulen

Assistant Professor (PI)

Universitair Medisch Centrum Utrecht

NETHERLANDS

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Philip D. King

University of Michigan Medical School

UNITED STATES

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Lauren Shechtman

Professional Research Assistant

University of Colorado Anschutz Medical Campus

UNITED STATES

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Andrew Leidal

Assistant Professor

University of Calgary

CANADA

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Jeroen Roose

Research Interests

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Articles (13)

Single cell proteomics characterization of bone marrow hematopoiesis with distinct Ras pathway lesions.

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH

Immediate myeloid depot for SARS-CoV-2 in the human lung

Cutting Edge: Induced Loss of Rasgrp1 in Peripheral CD4+ T Cells of Conditional Rasgrp1-Deficient Mice Reveals an Essential Role for Rasgrp1 in TCR/CD28-Induced Ras–MAPK Signaling

SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants

Investigating increased hematopoietic stem cell fitness in a novel mouse model

Tcof1 haploinsufficiency promotes early T cell precursor-like leukemia in NrasQ61R/+ mice

Cellular architecture of human brain metastases

Editorial overview: Communities in immune cell signaling

NrasQ61R/+ and Kras-/- cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors

T cells: a dedicated effector kinase pathways for every trait?

Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity

Regulation of the Small GTPase Ras and Its Relevance to Human Disease

Collaborators (6)

Irina Nazarenko

Abbas Doosti

Yvonne Vercoulen

Philip D. King

Lauren Shechtman

Andrew Leidal

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