Andrzej Bojarski

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Head of the department

Institute of Pharmacology

Poland

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About

Dr. Andrzej Bojarski is the Head of the Department at the Maj Institute of Pharmacology, Poland. His research focuses on the design and synthesis of multi-target antidepressants and new derivatives aimed at modulating mGlu 7 receptor activity. His recent publications highlight significant studies on serotonin transporters and the pharmacological properties of various receptor ligands.

Recent Grants

Grant: Close

Inhibition of Pseudomonas aeruginosa virulence as a putative new strategy against bacterial infection

Open Date: 2020-01-01

Close Date:

Grant: Close

Opracowanie unikalnych sond molekularnych: niskozasadowi agoniści do badania funkcji receptora 5-HT7.

Open Date: 2018-01-19

Close Date: 2021-01-18

Grant: Close

GABA-B receptor modulators with functional selectivity - a putative new class of antidepressant drugs

Open Date: 2018-01-01

Close Date:

Grant: Close

Nietypowe ligandy receptora 5-HT6

Open Date: 2015-02-04

Close Date: 2017-08-03

Grant: Close

EXtention of academia‐based PLATFORM to antidepressant hits discovery. Rozszerzenie badań Platformy akademickiej do poszukiwania związków o własnościach przeciwdepresyjnych.

Open Date: 2013-11-01

Close Date: 2016-10-30

Articles (10)

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (9)

Dawid Warszycki

Institute of Pharmacology

POLAND

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Agnieszka Nikiforuk

Maj Institute of Pharmacology Polish Academy of Sciences

POLAND

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Frédéric Lamaty

University of Montpellier

FRANCE

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Séverine Chaumont-Dubel

Assistant professor

University of Montpellier

FRANCE

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Vittorio Canale

Assistant Professor

Jagiellonian University

POLAND

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Paweł Zajdel

professor

Uniwersytet Jagiellonski Collegium Medicum

POLAND

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Elżbieta Pękala

Jagiellonian University Medical College

POLAND

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Xavier Bantreil

Associate Professor (HDR)

Institut des Biomolécules Max Mousseron

FRANCE

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Philippe Marin

University of Montpellier

FRANCE

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Andrzej Bojarski

Research Interests

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About

Recent Grants

Articles (10)

Design and Synthesis of Potential Multi-Target Antidepressants: Exploration of 1-(4-(7-Azaindole)-3,6-dihydropyridin-1-yl)alkyl-3-(1<i>H</i>-indol-3-yl)pyrrolidine-2,5-dione Derivatives with Affinity for the Serotonin Transporter

Impact of the Substitution Pattern at the Basic Center and Geometry of the Amine Fragment on 5-HT<sub>6</sub> and D<sub>3</sub>R Affinity in the 1<i>H</i>-pyrrolo[3,2-<i>c</i>]quinoline Series

Isomeric Activity Cliffs—A Case Study for Fluorine Substitution of Aminergic G Protein-Coupled Receptor Ligands

Design and Synthesis of New Quinazolin-4-one Derivatives with Negative mGlu<sub>7</sub> Receptor Modulation Activity and Antipsychotic-Like Properties

1-(Arylsulfonyl-isoindol-2-yl)piperazines as 5-HT<sub>6</sub>R Antagonists: Mechanochemical Synthesis, In Vitro Pharmacological Properties and Glioprotective Activity

Hydrogen Bonds with Fluorine in Ligand–Protein Complexes-the PDB Analysis and Energy Calculations

Hydrogen Bonds with Fluorine in Ligand-Protein Complexes-the PDB Analysis and Energy Calculations

Activation of the 5-HT7 receptor and MMP-9 signaling module in the hippocampal CA1 region is necessary for the development of depressive-like behavior

An Attempt to Achieve Hydrated Imidazoline Ring Expansion (HIRE) of Diarene-Fused [1,4]Diazepinones Delivers Selective Dopamine D-2 Receptor Ligands

In Vitro and In Silico Analysis of the Residence Time of Serotonin 5-HT7 Receptor Ligands with Arylpiperazine Structure: A Structure- Kinetics Relationship Study

Collaborators (9)

Dawid Warszycki

Agnieszka Nikiforuk

Frédéric Lamaty

Séverine Chaumont-Dubel

Vittorio Canale

Paweł Zajdel

Elżbieta Pękala

Xavier Bantreil

Philippe Marin

Make your next move.

Andrzej Bojarski

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (10)

Design and Synthesis of Potential Multi-Target Antidepressants: Exploration of 1-(4-(7-Azaindole)-3,6-dihydropyridin-1-yl)alkyl-3-(1<i>H</i>-indol-3-yl)pyrrolidine-2,5-dione Derivatives with Affinity for the Serotonin Transporter

Impact of the Substitution Pattern at the Basic Center and Geometry of the Amine Fragment on 5-HT<sub>6</sub> and D<sub>3</sub>R Affinity in the 1<i>H</i>-pyrrolo[3,2-<i>c</i>]quinoline Series

Isomeric Activity Cliffs—A Case Study for Fluorine Substitution of Aminergic G Protein-Coupled Receptor Ligands

Design and Synthesis of New Quinazolin-4-one Derivatives with Negative mGlu<sub>7</sub> Receptor Modulation Activity and Antipsychotic-Like Properties

1-(Arylsulfonyl-isoindol-2-yl)piperazines as 5-HT<sub>6</sub>R Antagonists: Mechanochemical Synthesis, In Vitro Pharmacological Properties and Glioprotective Activity

Hydrogen Bonds with Fluorine in Ligand&ndash;Protein Complexes-the PDB Analysis and Energy Calculations

Hydrogen Bonds with Fluorine in Ligand-Protein Complexes-the PDB Analysis and Energy Calculations

Activation of the 5-HT7 receptor and MMP-9 signaling module in the hippocampal CA1 region is necessary for the development of depressive-like behavior

An Attempt to Achieve Hydrated Imidazoline Ring Expansion (HIRE) of Diarene-Fused [1,4]Diazepinones Delivers Selective Dopamine D-2 Receptor Ligands

In Vitro and In Silico Analysis of the Residence Time of Serotonin 5-HT7 Receptor Ligands with Arylpiperazine Structure: A Structure- Kinetics Relationship Study

Collaborators (9)

Dawid Warszycki

Agnieszka Nikiforuk

Frédéric Lamaty

Séverine Chaumont-Dubel

Vittorio Canale

Paweł Zajdel

Elżbieta Pękala

Xavier Bantreil

Philippe Marin

Make your next move.

Hydrogen Bonds with Fluorine in Ligand–Protein Complexes-the PDB Analysis and Energy Calculations