Andy Tsai

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Stanford University School of Medicine

United States

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An effective therapeutic approach for Alzheimer's disease by targeting phospholipase C 𝛾 2

Open Date: 2021-01-01

Close Date: 2022-12-01

Articles (10)

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2020

Year:

2020

Collaborators (3)

Cristian Lasagna-Reeves

Assistant Professor

Indiana University School of Medicine

UNITED STATES

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Micaiah Atkins

Life Science Research Professional

Stanford University Medical Center

UNITED STATES

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Gary E. Landreth

Indiana University School of Medicine

UNITED STATES

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Andy Tsai

Research Interests

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Recent Grants

Articles (10)

Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer’s disease

The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer’s disease

Age-dependent microstructure alterations in 5xFAD mice by high-resolution diffusion tensor imaging.

Plcg2 M28L Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice.

PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer's disease.

The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model.

Moderate Ethanol Pre-treatment Mitigates ICH-Induced Injury via ER Stress Modulation in Rats.

Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration.

Metabolic Defects Caused by High-Fat Diet Modify Disease Risk through Inflammatory and Amyloidogenic Pathways in a Mouse Model of Alzheimer’s Disease

The Role of Urocortins in Intracerebral Hemorrhage

Collaborators (3)

Cristian Lasagna-Reeves

Micaiah Atkins

Gary E. Landreth

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