Cristian Lasagna-Reeves

Assistant Professor

Indiana University School of Medicine

United States

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Dr. Cristian Lasagna-Reeves is an Assistant Professor at Indiana University School of Medicine in the United States. His research focuses on tauopathies, Alzheimer's disease, and the role of microglia and astrocytes in neurodegenerative processes. Recent publications include studies on tau phosphorylation, microglial response modulation, and the impact of astrocytes on synaptic toxicity, contributing to a deeper understanding of neurodegenerative mechanisms.

Articles (7)

Year:

2025

Year:

2024

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2023

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2022

Year:

2022

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UNITED STATES

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Cristian Lasagna-Reeves

Research Interests

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Articles (7)

Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation

TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse model

TREM2-Deficient Microglia Attenuate Tau Spreading In Vivo

The reduction of astrocytic tau prevents amyloid-β-induced synaptotoxicity

The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer’s disease

Pathological tau and reactive astrogliosis are associated with distinct functional deficits in a mouse model of tauopathy

A1 reactive astrocytes and a loss of TREM2 are associated with an early stage of pathology in a mouse model of cerebral amyloid angiopathy

Collaborators (5)

Jungsu Kim

Bradley Hyman

Jean-Christophe Rochet

Andy Tsai

Gary E. Landreth

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