Anne Nichols

Research Assistant Professor

University of Rochester Medical Center

United States

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About

Anne Nichols is a Research Assistant Professor at the University of Rochester Medical Center in the United States. Her research focuses on tendon healing, fibrosis, and the cell dynamics involved in these processes, as evidenced by her recent publications on progenitor cells, nanoparticle drug delivery systems, and macrophage roles in tendon regeneration. She is particularly interested in the molecular mechanisms that govern tendon homeostasis and healing responses.

Articles (9)

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2025

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2025

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2024

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2024

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2024

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2023

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2022

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Anne Nichols

Research Interests

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Articles (9)

Epitenon-derived progenitors drive fibrosis and regeneration after flexor tendon injury in a spatially-dependent manner

Ogerin induced activation of Gpr68 alters tendon healing

Development of a nanoparticle-based tendon-targeting drug delivery system to pharmacologically modulate tendon healing

Correction: Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype

Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing

Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype

CCR2 is expressed by tendon resident macrophage and T cells, while CCR2 deficiency impairs tendon healing via blunted involvement of tendon‐resident and circulating monocytes/macrophages

Impact of isolation method on cellular activation and presence of specific tendon cell subpopulations during in vitro culture

NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival

Collaborators (5)

Mark Buckley

Danielle Benoit

Jennifer Jonason

Warren C. Hammert

Alayna E. Loiselle

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