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Antonio Rodriguez-Sinovas

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Senior Scientist

Vall d'Hebron Institut de Recerca

Spain

Research Interests

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Recent Grants

Grant: Open

Desentrañando los efectos cardiotóxicos de los micro/nanoplásticos en corazones sanos y con patología previa.

Open Date: 2027-01-01

Close Date: 2030-12-01

Grant: Open

Inhibición del intercambiador sodio/calcio mitochondrial, NCLX, como estrategia para reducer el daño miocárdico por isquemia-reperfusión durante un infarto de miocardio.

Open Date: 2025-01-01

Close Date: 2026-12-01

Grant: Open

El intercambiador sodio/calcio mitochondrial, NCLX, como diana terapéutica contra el daño miocárdico por isquemia-reperfusión durante un infarto de miocardio.

Open Date: 2025-01-01

Close Date: 2026-12-01

Grant: Open

Inhibition of mitochondrial sodium/calcium exchanger, NCLX, as a therapeutic strategy to reduce myocardial ischemia-reperfusion injury during myocardial infarction.

Open Date: 2024-01-01

Close Date: 2026-12-01

Grant: Close

El enzima lisil oxidasa (LOX) en la aterosclerosis y la calcificación: estudio en un modelo de aterosclerosis experimental y en válvulas aórticas humanas calcificadas.

Open Date: 2023-01-01

Close Date: 2023-12-01

Articles (16)

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2022

Collaborators (10)

Dominique de Kleijn

Professor

UMC Utrecht

NETHERLANDS

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Heiko Herwald

Lund University

SWEDEN

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Harry Björkbacka

Lund University

SWEDEN

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Montserrat Batlle

researcher

Institut d'Investigacions Biomèdiques August Pi i Sunyer

SPAIN

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Imanol Otaegui Irurueta

Profesor asociado

Universitat Autònoma de Barcelona (UAB)

SPAIN

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Antonio Rodriguez-Sinovas

Research Interests

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Recent Grants

Articles (16)

Calpain-2 inhibition prevents pressure overload–induced lysosomal cathepsin release and cardiac hypertrophy

Diesel exhaust particles induce a two-stage program of myocardial oxidative stress involving NADPH oxidases and mitochondrial dysfunction: Modulation by CeO2 nanoparticles

Glycative Stress Disrupts the Mitochondrial‐Lysosome Axis and Promotes Geroconversion in Aging Cardiomyocytes

Microbiome multi-omics analysis reveals novel biomarkers and mechanisms linked with CD etiopathology

Insights into the causal role of diesel exhaust particles in ventricular arrhythmogenesis: protective effects of antioxidant cerium oxide nanoparticles

Involvement of connexin 43 in myocardial ischemia–reperfusion injury

Inhibition of ATP-citrate lyase by bempedoic acid protects against abdominal aortic aneurysm formation in mice

TRPV4 Channels Promote Pathological, but Not Physiological, Cardiac Remodeling through the Activation of Calcineurin/NFAT and TRPC6

The IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT): multicenter pig study on the effect of ischemic preconditioning

Efficacy of a cysteine protease inhibitor compared with enalapril in murine heart failure models

Connexin 43 modulates reverse electron transfer in cardiac mitochondria from inducible knock-out Cx43Cre−ER(T)/fl mice by altering the coenzyme Q pool

Long-Term Protective Effects of Succinate Dehydrogenase Inhibition during Reperfusion with Malonate on Post-Infarction Left Ventricular Scar and Remodeling in Mice

Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction

Spontaneous reperfusion enhances succinate concentration in peripheral blood from stemi patients but its levels does not correlate with myocardial infarct size or area at risk.

Lysyl oxidase-dependent extracellular matrix crosslinking modulates calcification in atherosclerosis and aortic valve disease

Activation of Wnt/β-catenin signaling in abdominal aortic aneurysm: A potential therapeutic opportunity?

Collaborators (10)

Dominique de Kleijn

Heiko Herwald

Harry Björkbacka

Montserrat Batlle

Imanol Otaegui Irurueta

NATALIA BORRUEL

Manichanh Chaysavanh

Eduard Guasch

Lina Badimon

Ernesto Martinez-Martinez

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