Dominique de Kleijn

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Professor

UMC Utrecht

Netherlands

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About

Dominique de Kleijn is a Professor at UMC Utrecht in the Netherlands. His research focuses on cardiovascular health, particularly on the characteristics of carotid plaques, the assessment of cardioprotective therapies, and the epigenetic aspects of atherosclerosis. Recent articles authored by him explore the impact of ischemic preconditioning and the association of biomarkers with cardiovascular events in patients. His work contributes to understanding the dynamics of endothelial damage and lipid profiles in cardiovascular disease.

Recent Grants

Grant: Close

Taxinomisis

Open Date: 2018-01-01

Close Date: 2022-01-01

Grant: Close

pERSUASIVE

Open Date: 2017-12-01

Close Date: 2020-12-01

Grant: Close

EXOSOMES FOR DIAGNOSIS AND TREATMENT OF ISCHEMIC HEART DISEASE

Open Date: 2017-12-01

Close Date: 2020-12-01

Articles (8)

Year:

2025

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2021

Collaborators (4)

Sander W. van der Laan

Assistant Professor

University Medical Center Groningen

NETHERLANDS

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Yong-Gui Gao

Nanyang Technological University (NTU)

SINGAPORE

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Ernest Diez Benavente

Assistant Professor

University Medical Center Groningen

NETHERLANDS

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Jeffrey Kroon

Assistant Professor, Staff

Amsterdam UMC Locatie AMC

NETHERLANDS

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Dominique de Kleijn

Research Interests

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About

Recent Grants

Articles (8)

Carotid Plaques Show More Unstable Characteristics Between 2010 and 2021 After a Prior Decade of Stabilization

Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans

The IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT): multicenter pig study on the effect of ischemic preconditioning

Plasma Lipoprotein Lipase Is Associated with Risk of Future Major Adverse Cardiovascular Events in Patients Following Carotid Endarterectomy

Endothelial Damage Arising From High Salt Hypertension Is Elucidated by Vascular Bed Systematic Profiling

Plasma Extracellular Vesicle Serpin G1 and CD14 Levels are Associated with Major Adverse Cardiovascular Events and Major Adverse Limb Events in Patients Undergoing Femoral Endarterectomy

Ceramides and phospholipids in plasma extracellular vesicles are associated with high risk of major cardiovascular events after carotid endarterectomy.

Experimental parameters and infarct size in closed chest pig LAD ischemia reperfusion models; lessons learned

Collaborators (4)

Sander W. van der Laan

Yong-Gui Gao

Ernest Diez Benavente

Jeffrey Kroon

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