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Asier Sáez-Cirión

Institut Pasteur

France

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Research Interests

Immunology

100%

Virology

100%

Hiv

100%

T Cell Biology

90%

Antiviral Therapy

60%

Immune Response

50%

Antiretroviral Therapy

50%

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Articles22

A genetic fingerprint associated with durable HIV remission after interruption of antiretroviral treatment: ANRS VISCONTI/PRIMO.

Article Link

Year:

2025

Impact of rosuvastatin on the memory potential and functionality of CD8+ T cells from people with HIV

Article Link

Year:

2025

Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells

Article Link

Year:

2024

Distinct SIV-specific CD8 T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence.

Article Link

Year:

2024

High concentrations of Maraviroc do not alter immunological and metabolic parameters of CD4 T cells.

Article Link

Year:

2024

Dynamics of virological and immunological markers of HIV persistence after allogeneic haematopoietic stem-cell transplantation in the IciStem cohort: a prospective observational cohort study.

Article Link

Year:

2024

Early antiretroviral therapy favors post-treatment SIV control associated with the expansion of enhanced memory CD8+ T-cells.

Article Link

Year:

2024

Antiviral capacity of the early CD8 T-cell response is predictive of natural control of SIV infection: Learning in vivo dynamics using ex vivo data.

Article Link

Year:

2024

Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller

Article Link

Year:

2023

In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Article Link

Year:

2023

Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection.

Article Link

Year:

2023

In-Depth Characterization of Full-Length Archived Viral Genomes after Nine Years of Posttreatment HIV Control

Article Link

Year:

2023

Highlights from the Inaugural HIV Reservoirs and Immune Control Conference, October 1st-4th 2023, Malahide Ireland.

Article Link

Year:

2023

CD8 + T-cell priming is quantitatively but not qualitatively impaired in people with HIV-1 on antiretroviral therapy.

Article Link

Year:

2023

[A shot of synTac to activate CD8+ T cells cytotoxic specific response against HIV].

Article Link

Year:

2023

Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers

Article Link

Year:

2022

Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells

Article Link

Year:

2022

Prolonged Antiretroviral Treatment Induces Adipose Tissue Remodelling Associated with Mild Inflammation in SIV-Infected Macaques.

Article Link

Year:

2022

NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infections

Article Link

Year:

2022

Novel role of UHRF1 in the epigenetic repression of the latent HIV-1

Article Link

Year:

2022

Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control

Article Link

Year:

2022

Expansion of Immature Neutrophils During SIV Infection Is Associated With Their Capacity to Modulate T-Cell Function

Article Link

Year:

2022

Collaborators18

Aurélie Barrail-Tran

Université Paris-Saclay

FRANCE

Jordan D. Dimitrov

Sorbonne Université

FRANCE

Virginie Gautier

Associate Professor in Virology

Dublin City University

IRELAND

Maria Salgado

SPAIN

Hugo MOUQUET

Université Paris Cité

FRANCE

Roger Le Grand

Head of IDMIT Department

CEA

FRANCE

Eduard Baquero

Institut Pasteur

FRANCE

Maxime HENTZIEN

Full Professor in Infectious Diseases

Université de Reims Champagne-Ardenne

FRANCE

Estelle Plant

Université libre de Bruxelles

BELGIUM

Gregor Hutter

SWITZERLAND

Luis M Molinos-Albert

Barcelona Institute for Global Health

SPAIN

Javier Martinez-Picado

Associate professor

SPAIN

David Gordon

Assistant Professor

Emory University

UNITED STATES

Laurent Decosterd

Head of the Laboratory of Clinical Pharmacology / Associated Professor

Centre Hospitalier Universitaire Vaudois

SWITZERLAND

Jurgen Kuball

UMC Utrecht

NETHERLANDS

Olivier Schwartz

FRANCE

Francis Corazza

Université libre de Bruxelles

BELGIUM

Carine Van Lint

Université libre de Bruxelles (ULB)

BELGIUM

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Asier Sáez-Cirión

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Research Interests

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Articles22

A genetic fingerprint associated with durable HIV remission after interruption of antiretroviral treatment: ANRS VISCONTI/PRIMO.

Impact of rosuvastatin on the memory potential and functionality of CD8+ T cells from people with HIV

Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells

Distinct SIV-specific CD8 T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence.

High concentrations of Maraviroc do not alter immunological and metabolic parameters of CD4 T cells.

Dynamics of virological and immunological markers of HIV persistence after allogeneic haematopoietic stem-cell transplantation in the IciStem cohort: a prospective observational cohort study.

Early antiretroviral therapy favors post-treatment SIV control associated with the expansion of enhanced memory CD8<sup>+</sup> T-cells.

Antiviral capacity of the early CD8 T-cell response is predictive of natural control of SIV infection: Learning in vivo dynamics using ex vivo data.

Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller

In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8<sup>+</sup> T cells in HIV infection.

In-Depth Characterization of Full-Length Archived Viral Genomes after Nine Years of Posttreatment HIV Control

Highlights from the Inaugural HIV Reservoirs and Immune Control Conference, October 1<sup>st</sup>-4<sup>th</sup> 2023, Malahide Ireland.

CD8 + T-cell priming is quantitatively but not qualitatively impaired in people with HIV-1 on antiretroviral therapy.

[A shot of synTac to activate CD8<sup>+</sup> T cells cytotoxic specific response against HIV].

Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers

Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells

Prolonged Antiretroviral Treatment Induces Adipose Tissue Remodelling Associated with Mild Inflammation in SIV-Infected Macaques.

NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infections

Novel role of UHRF1 in the epigenetic repression of the latent HIV-1

Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control

Expansion of Immature Neutrophils During SIV Infection Is Associated With Their Capacity to Modulate T-Cell Function

Collaborators18

Aurélie Barrail-Tran

Jordan D. Dimitrov

Virginie Gautier

Maria Salgado

Hugo MOUQUET

Roger Le Grand

Eduard Baquero

Maxime HENTZIEN

Estelle Plant

Gregor Hutter

Luis M Molinos-Albert

Javier Martinez-Picado

David Gordon

Laurent Decosterd

Jurgen Kuball

Olivier Schwartz

Francis Corazza

Carine Van Lint

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