Bianca Fiorillo

Non-tenured Assistant Professor-RTDA

University of Naples Federico II

Italy

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Bianca Fiorillo is a Non-tenured Assistant Professor-RTDA at the University of Naples Federico II, Italy. Her research focuses on the development of novel pharmacological modulators for liver fibrosis and the investigation of GPBAR1 and LIFR interactions. She has published recent articles on topics including the design of dual FXR-LIFR modulators and the application of artificial intelligence in ligand discovery.

Articles (12)

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2025

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

Collaborators (8)

F. Javier Luque

University of Barcelona

SPAIN

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Bruno Catalanotti

Assistant Professor

University of Naples Federico II

ITALY

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Angela Zampella

ITALY

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Marta Filizola

Dean

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Claudia Finamore

University of Naples Federico II

ITALY

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stefano fiorucci

University of Perugia

ITALY

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Vittorio Limongelli

Full Professor

Università del Salento

SWITZERLAND

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Simona De Marino

ITALY

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Bianca Fiorillo

Research Interests

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Articles (12)

Harnessing the Estradienone Scaffold to Develop Dual GPBAR1 and LIFR Modulators for Liver Fibrosis

Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R

Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis

Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders

Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists

Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders

Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”

Molecular Basis for Non-Covalent, Non-Competitive FAAH Inhibition

Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease

Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics

Combinatorial targeting of GPBAR1 and CYSLTR1 reveals a mechanistic role for bile acids and leukotrienes in drug induced liver injury

Metadynamics simulations leveraged by statistical analyses and artificial intelligence-based tools to inform the discovery of G protein-coupled receptor ligands

Collaborators (8)

F. Javier Luque

Bruno Catalanotti

Angela Zampella

Marta Filizola

Claudia Finamore

stefano fiorucci

Vittorio Limongelli

Simona De Marino

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