Bing Yao

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Associate Professor

Emory University

United States

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About

Dr. Bing Yao is an Associate Professor at Emory University in the United States. His research focuses on the interplay between epigenetic modifications and neurological diseases, particularly Alzheimer’s disease and glioblastoma. His recent publications include investigations into R-loop induction by Zika virus, the role of hydroxymethylcytosine in Alzheimer’s pathology, and advancements in single-cell chromatin accessibility analysis.

Recent Grants

Grant: Close

Epigenetic roles of DNA adenine methylation in Alzheimer's Disease

Open Date: 2019-08-01

Close Date: 2024-03-31

Grant: Close

Epigenetic roles of DNA adenine methylation in stress response

Open Date: 2019-04-01

Close Date: 2023-12-31

Articles (19)

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2021

Collaborators (7)

David Gilbert

Professor

San Diego Biomedical Research Institute

UNITED STATES

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Peng Jin

Emory University

UNITED STATES

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Yue Feng

Professor

Emory University

UNITED STATES

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jing wang

University of California, San Francisco

UNITED STATES

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Jian-Feng Xiang

Emory University

UNITED STATES

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Xin Ma

University of Florida

UNITED STATES

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Li Chen

Associate Professor

University of Florida

UNITED STATES

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Bing Yao

Research Interests

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About

Recent Grants

Articles (19)

Interferon-dependent R-loop induction by Zika virus contributes to growth attenuation

Brain 5-hydroxymethylcytosine alterations are associated with Alzheimer's disease neuropathology.

Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma.

Bridging the gap: R-loop mediated genomic instability and its implications in neurological diseases

TDP-43 chronic deficiency leads to dysregulation of transposable elements and gene expression by affecting R-loop and 5hmC crosstalk

Isoform balance of the long noncoding RNA NEAT1 is regulated by the RNA-binding protein QKI, governs the glioma transcriptome, and impacts cell migration

Deep5hmC: predicting genome-wide 5-hydroxymethylcytosine landscape via a multimodal deep learning model

scaDA: A novel statistical method for differential analysis of single-cell chromatin accessibility sequencing data

Identification of pathological pathways centered on circRNA dysregulation in association with irreversible progression of Alzheimer's disease.

Identification of brain region-specific landscape and functions of clustered circRNAs in Alzheimer's disease using circMeta2.

Epigenetic modifications of DNA and RNA in Alzheimer's disease.

Social defeat stress induces genome-wide 5mC and 5hmC alterations in the mouse brain

The human lncRNA GOMAFU suppresses neuronal interferon response pathways affected in neuropsychiatric diseases

Brain methylome remodeling selectively regulates neuronal activity genes linking to emotional behaviors in mice exposed to maternal immune activation

Accurate identification of circRNA landscape and complexity reveals their pivotal roles in human oligodendroglia differentiation

Expression of expanded GGC repeats within <i>NOTCH2NLC</i> causes behavioral deficits and neurodegeneration in a mouse model of neuronal intranuclear inclusion disease

Multi-task deep autoencoder to predict Alzheimer’s disease progression using temporal DNA methylation data in peripheral blood

Reversing neural circuit and behavior deficit in mice exposed to maternal inflammation by Zika␣virus.

5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer's disease.

Collaborators (7)

David Gilbert

Peng Jin

Yue Feng

jing wang

Jian-Feng Xiang

Xin Ma

Li Chen

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