Bluma J Lesch

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Associate Professor

Yale University

United States

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Bluma J Lesch is an Associate Professor at Yale University in the United States. Her research focuses on transcriptional regulation, chromatin accessibility, and the biological mechanisms underlying male meiosis and fertility. Recent publications include studies on H3K4 methylation, bioinformatics of myelin-microbe interactions, and evolutionary innovations in germline biology.

Recent Grants

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Genome-epigenome interactions in heritable lung cancer risk

Open Date: 2024-01-01

Close Date: 2025-12-31

Articles (7)

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2025

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2025

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2025

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2024

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2024

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2023

Year:

2023

Collaborators (1)

Gunter Wagner

Professor Emeritus

Yale University

UNITED STATES

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Bluma J Lesch

Research Interests

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About

Recent Grants

Articles (7)

Evolutionary innovations in germline biology of placental mammals identified by transcriptomics of first wave spermatogenesis in opossum

H3K4me3 amplifies transcription at intergenic active regulatory elements

SMARCA5 restricts chromatin accessibility to promote male meiosis and fertility in mammals

Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis

Functional Roles of H3K4 Methylation in Transcriptional Regulation

DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres

DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement

Collaborators (1)

Gunter Wagner

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