Gunter Wagner

Professor Emeritus

Yale University

United States

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Gunter Wagner is a Professor Emeritus at Yale University in the United States. His research focuses on evolutionary biology, specifically in areas such as cell type homologies, protein fitness estimation, and innovations in mammalian pregnancy. Recent articles have explored topics including the evolutionary biology of placental mammals and metabolic interactions within tissues. His work provides significant insights into gene expression and its implications for reproductive health.

Articles (20)

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2025

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2020

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2020

Collaborators (13)

Irene Pak

University of California, San Francisco

UNITED STATES

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Yansheng Liu

Assistant Professor

Yale University School of Medicine

UNITED STATES

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P. J. Bergmann

UNITED STATES

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Bluma J Lesch

Associate Professor

Yale University

UNITED STATES

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Lee Koren

ISRAEL

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Nagendra Monangi

Associate Professor of Pediatrics

Cincinnati Children's Hospital Medical Center

UNITED STATES

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Marilyn Renfree

Melbourne Laureate Professor

University of Melbourne

AUSTRALIA

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Mihaela Pavlicev

Universität Wien

AUSTRIA

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Alan Love

University of Minnesota

UNITED STATES

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Yueh-Chiang Hu

Associate Professor/Director of Transgenic Animal and Genome Editing Core

Cincinnati Children's Hospital Medical Center

UNITED STATES

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Vincent Lynch

Assistant Professor

University at Buffalo

UNITED STATES

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Junaid Afzal

Associate Professoinal Research

UCSF Medical Center

UNITED STATES

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Oliver Griffith

Lecturer

Macquarie University

AUSTRALIA

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Gunter Wagner

Research Interests

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Articles (20)

The application of irreversible genomic states to define and trace ancient cell type homologies

Pseudo-perplexity in one fell swoop for protein fitness estimation

Cell type and cell signalling innovations underlying mammalian pregnancy

Evolutionary innovations in germline biology of placental mammals identified by transcriptomics of first wave spermatogenesis in opossum

A common allele increases endometrial Wnt4 expression, with antagonistic implications for pregnancy, reproductive cancers, and endometriosis

Metabolic complementation between cells drives the evolution of tissues and organs

The extension of mammalian pregnancy required taming inflammation: Independent evolution of extended placentation in the tammar wallaby

The mammary hair of Monodelphis domestica and homology of the mammary pilosebacous unit

Reading the palimpsest of cell interactions: What questions may we ask of the data?

Experimental and phylogenetic evidence for correlated gene expression evolution in endometrial and skin fibroblasts

Stress, harshness, and evolutionary history

The hierarchical basis of serial homology and evolutionary novelty

The value of broad taxonomic comparisons in evolutionary medicine: Disease is not a trait but a state of a trait!

Proteotype coevolution and quantitative diversity across 11 mammalian species

Co‐option of stress mechanisms in the origin of evolutionary novelties

Body Plan Identity: A Mechanistic Model

Tracing the cis-regulatory changes underlying the endometrial control of placental invasion

Cooption of polyalanine tract into a repressor domain in the mammalian transcription factor HoxA11

Evolution of embryo implantation was enabled by the origin of decidual stromal cells in eutherian mammals

Using 3D‐digital photogrammetry to examine scaling of the body axis in burrowing skinks

Collaborators (13)

Irene Pak

Yansheng Liu

P. J. Bergmann

Bluma J Lesch

Lee Koren

Nagendra Monangi

Marilyn Renfree

Mihaela Pavlicev

Alan Love

Yueh-Chiang Hu

Vincent Lynch

Junaid Afzal

Oliver Griffith

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