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Bo Porse

Københavns Universitet

Denmark

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Research Interests

Cell Biology

100%

Immunology

50%

Epigenetic

50%

Hematopoiesis

40%

Cancer Biology

40%

Histone Biology

30%

Gene Silencing

30%

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Articles21

Mutant CEBPA promotes tolerance to inflammatory stress through deficient AP-1 activation

Article Link

Year:

2025

Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics

Article Link

Year:

2025

A non-conditioned bone marrow transplantation mouse model to study clonal hematopoiesis and myeloid malignancies

Article Link

Year:

2025

Quantitative Label-Free Single-Cell Proteomics on the Orbitrap Astral MS

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Year:

2025

Overlapping DNA methylation changes in enhancers in clonal cytopenia of undetermined significance and myelodysplastic neoplasm patients with TET2, IDH2, or DNMT3A mutations

Article Link

Year:

2025

Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells

Article Link

Year:

2024

Increased myeloid‐derived suppressor cell activation in clonal cytopenia of undetermined significance and low‐risk myelodysplastic syndrome

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Year:

2024

BloodSpot 3.0

Article Link

Year:

2024

A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis

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Year:

2024

The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

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Year:

2023

The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters

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Year:

2023

LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

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Year:

2023

Inter and transgenerational impact of H3K4 methylation in neuronal homeostasis

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Year:

2023

ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of Il9 during Allergic Lung Inflammation

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Year:

2023

TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

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Year:

2023

Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition

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Year:

2023

H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway

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Year:

2022

Real-Time Search-Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics

Article Link

Year:

2022

Progression of the pluripotent epiblast depends upon the NMD factor UPF2

Article Link

Year:

2022

Dynamic intron retention modulates gene expression in the monocytic differentiation pathway

Article Link

Year:

2022

Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis

Article Link

Year:

2022

Collaborators38

Sergi Cuartero

Josep Carreras Leukaemia Research Institute

SPAIN

Mette Louise Trempenau

Københavns Universitet

DENMARK

Kim Theilgaard-Mönch

Københavns Universitet

DENMARK

Seyed Mojtaba Ghiasi

Københavns Universitet

DENMARK

Anne Wenzel

Københavns Universitet

DENMARK

Mikkel Bruhn Schuster

Københavns Universitet

DENMARK

Pedro Aragon-Fernandez

Technical University of Denmark

DENMARK

Natalie J. Jooss

University of Oxford

UNITED KINGDOM

Sachin Pundhir

Københavns Universitet

DENMARK

Kristoffer Vitting-Seerup

Technical University of Denmark

DENMARK

Erwin Marten Schoof

Technical University of Denmark

DENMARK

Stine Ulrik Mikkelsen

Københavns Universitet

DENMARK

Nil Üresin

Københavns Universitet

DENMARK

Bauke de Boer

Assistent Professor

University of Copenhagen Biotech Research and Innovation Centre

DENMARK

Jakob Woessmann

Technical University of Denmark

DENMARK

Jennifer Chousal

University of California, San Diego

UNITED STATES

Ying Ge

Københavns Universitet

DENMARK

Paul Bourgine

forskargruppsledare (group leader)

Lund University

SWEDEN

Kristian Helin

CEO, Professor

Institute of Cancer Research

UNITED KINGDOM

Graeme M. Birdsey

Imperial College London

UNITED KINGDOM

Anne-Katrine Frank

Københavns Universitet

DENMARK

Mads Hald Andersen

Professor, dr.techn., Director

DENMARK

Sarah Line Skovbakke

Technical University of Denmark

DENMARK

Charlotte Brierley

Sloan Kettering Institute

UNITED STATES

Steffen Nørgaard

Københavns Universitet

DENMARK

Christina Simoglou Karali

University of Oxford

UNITED KINGDOM

Mark Kaplan

Professor

Indiana University School of Medicine

UNITED STATES

Sofia Bentivegna

University of Copenhagen

DENMARK

Linn Gillberg

DENMARK

Justin Wong

Senior Lecturer

Centenary Institute

AUSTRALIA

Anna Elisabetta Salcini

Københavns Universitet

DENMARK

Frederik Otzen Bagger

Head of Bioinformatics

Rigshospitalet

DENMARK

Jens Høiriis Nielsen

Københavns Universitet

DENMARK

Ole N. Jensen

DENMARK

Gergo Kovacs

Technical University of Denmark

DENMARK

Heidi Cook-Andersen

University of California

UNITED STATES

John E. J. Rasko

AUSTRALIA

Kedar Nath Natarajan

Principal Investigator/Associate Professor

Technical University of Denmark

DENMARK

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