Natalie J. Jooss

University of Oxford

United Kingdom

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Articles (16)

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2025

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2024

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (26)

Asif Iqbal

University of Birmingham

UNITED KINGDOM

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Mark Thomas

University of Birmingham

UNITED KINGDOM

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Johan Heemskerk

Emeritus Prof. of Cell Biochemistry of Thrombosis and Haemostasis

University of Maastricht

NETHERLANDS

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Lara Boerenkamp

University of Maastricht

NETHERLANDS

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Samantha Montague

University of Birmingham

UNITED KINGDOM

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Erwin Marten Schoof

Technical University of Denmark

DENMARK

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Steve P. Watson

UNITED KINGDOM

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Bo Porse

Københavns Universitet

DENMARK

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Johan Duchene

Associate Professor - Group Leader

Ludwig-Maximilians-Universität München

GERMANY

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Luis Arturo Moran Lara

University of Bristol

UNITED KINGDOM

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Stijn Agten

University of Maastricht

NETHERLANDS

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Charlotte Brierley

Sloan Kettering Institute

UNITED STATES

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Joanne Clark

University of Birmingham

UNITED KINGDOM

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Alexandre Slater

Dr at University of Birmingham

University of Birmingham

UNITED KINGDOM

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Christina Simoglou Karali

University of Oxford

UNITED KINGDOM

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Ingrid Dijkgraaf

University of Maastricht

NETHERLANDS

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Kanin Wichapong

University of Maastricht

NETHERLANDS

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Barrie Kellam

Professor of Medicinal Chemistry

University of Nottingham

UNITED KINGDOM

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Jonas Emsley

professor of macromolecular crystallography

University of Nottingham

UNITED KINGDOM

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Benjamin Schuster-Böckler

University of Oxford

UNITED KINGDOM

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Eleyna Martin

University of Birmingham

UNITED KINGDOM

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Natalie Poulter

University of Birmingham

UNITED KINGDOM

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Yvonne Döring

Professor Translational Research

Inselspital Universitätsspital Bern

SWITZERLAND

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Julie Rayes

Associate Professor & British Heart Foundation intermediate fellow

University of Birmingham

UNITED KINGDOM

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Constance Baaten

University of Maastricht

NETHERLANDS

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Richard Farndale

Chief Scientific Officer

UNITED KINGDOM

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Natalie J. Jooss

Research Interests

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Articles (16)

Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA.

Generating human bone marrow organoids for disease modeling and drug discovery

A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis

Restraining of glycoprotein VI- and integrin α2β1-dependent thrombus formation by platelet PECAM1

Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice

Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization

Pharmacological Inhibition of Glycoprotein VI- and Integrin α2β1-Induced Thrombus Formation Modulated by the Collagen Type

Platelet glycoprotein VI cluster size is related to thrombus formation and phosphatidylserine exposure in collagen-adherent platelets under arterial shear

Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling, and thrombus formation.

CLEC-2 supports platelet aggregation in mouse but not human blood at arterial shear.

Multiparameter platelet function analysis of bleeding patients with a prolonged platelet function analyser closure time

Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under Shear

MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice.

Platelets fine-tune effector responses of naïve CD4<sup>+</sup> T cells via platelet factor 4-regulated transforming growth factor β signaling.

Targeting platelet-derived CXCL12 impedes arterial thrombosis.

Galectin-9 activates platelet ITAM receptors Glycoprotein VI and C-type Lectin-Like Receptor-2.

Collaborators (26)

Asif Iqbal

Mark Thomas

Johan Heemskerk

Lara Boerenkamp

Samantha Montague

Erwin Marten Schoof

Steve P. Watson

Bo Porse

Johan Duchene

Luis Arturo Moran Lara

Stijn Agten

Charlotte Brierley

Joanne Clark

Alexandre Slater

Christina Simoglou Karali

Ingrid Dijkgraaf

Kanin Wichapong

Barrie Kellam

Jonas Emsley

Benjamin Schuster-Böckler

Eleyna Martin

Natalie Poulter

Yvonne Döring

Julie Rayes

Constance Baaten

Richard Farndale

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