Bozena Dziadek

academic teacher; researcher/PhD; Associate professor

University of Łódź

Poland

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About

Bozena Dziadek is an Associate Professor at the University of Łódź, Poland. Her research focuses on the development of novel antimycobacterial agents and their mechanisms of action, particularly targeting the enoyl acyl carrier protein reductase (InhA). Recent publications highlight her work on quinoline derivatives, heterocycles, and the functional responses of macrophages to Mycobacterium tuberculosis infection.

Articles (16)

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (12)

Bartłomiej Ferra

assistant professor

University of Gdańsk

POLAND

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Adrian Bekier

Assistant Professor

Medical University of Lodz

POLAND

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Jakub Kryczka

Institute for Medical Biology

POLAND

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Radoslaw Bednarek

assistant professor

Medical University of Lodz

POLAND

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Justyna Gatkowska

Associate Professor

University of Łódź

POLAND

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Malwina Kawka

University of Łódź

POLAND

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Lucyna Holec-Gąsior

Associate Professor

Gdańsk University of Technology, Faculty of Chemistry

POLAND

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Jakub Lach

University of Łódź

POLAND

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Marcin Słomka

University of Łódź

POLAND

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Jaroslaw Dziadek

Prof.

Polish Academy of Sciences

POLAND

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Katarzyna Dzitko

Deputy Dean of the Faculty of Biology and Environmental Protection / PhD, DSc, Assoc. Prof. (ENG) dr hab. prof. nadzw. UŁ (PL) / Director of the BioMedChem Doctoral School of the UL and Lodz Institutes of the Polish Academy of Science

University of Łódź

POLAND

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Przemyslaw Plocinski

adjunct professor

University of Łódź

POLAND

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Bozena Dziadek

Research Interests

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Articles (16)

New coumarin linked thiazole derivatives as antimycobacterial agents: Design, synthesis, enoyl acyl carrier protein reductase (InhA) inhibition and molecular modeling

Identification of new anti-mycobacterial agents based on quinoline-isatin hybrids targeting enoyl acyl carrier protein reductase (InhA)

Identification of 2-(N-aryl-1,2,3-triazol-4-yl) quinoline derivatives as antitubercular agents endowed with InhA inhibitory activity

Benzenesulfonohydrazide-tethered non-fused and fused heterocycles as potential anti-mycobacterial agents targeting enoyl acyl carrier protein reductase (InhA) with antibiofilm activity

Evaluation of long-term immunity and protection against T. gondii after immunization with multivalent recombinant chimeric T. gondii proteins

Depletion of tRNA CCA ‑ adding enzyme in Mycobacterium tuberculosis leads to polyadenylation of transcripts and precursor tRNAs

The functional response of human monocyte-derived macrophages to serum amyloid A and Mycobacterium tuberculosis infection

2,4-Disubstituted pyridine derivatives are effective against intracellular and biofilm-forming tubercle bacilli

4-Arylthiosemicarbazide Derivatives as Toxoplasmic Aromatic Amino Acid Hydroxylase Inhibitors and Anti-inflammatory Agents

The Orphan Response Regulator Rv3143 Modulates the Activity of the NADH Dehydrogenase Complex (Nuo) in Mycobacterium tuberculosis via Protein–Protein Interactions

Imidazole-Thiosemicarbazide Derivatives as Potent Anti-Mycobacterium tuberculosis Compounds with Antibiofilm Activity

Mycobacterium tuberculosis Binds Human Serum Amyloid A, and the Interaction Modulates the Colonization of Human Macrophages and the Transcriptional Response of the Pathogen

Dissecting the RecA-(In)dependent Response to Mitomycin C in Mycobacterium tuberculosis Using Transcriptional Profiling and Proteomics Analyses

The Immunogenic and Immunoprotective Activities of Recombinant Chimeric T. gondii Proteins Containing AMA1 Antigen Fragments

PPE51 Is Involved in the Uptake of Disaccharides by Mycobacterium tuberculosis.

Toxoplasma gondii Recombinant antigen AMA1: Diagnostic Utility of Protein Fragments for the Detection of IgG and IgM Antibodies

Collaborators (12)

Bartłomiej Ferra

Adrian Bekier

Jakub Kryczka

Radoslaw Bednarek

Justyna Gatkowska

Malwina Kawka

Lucyna Holec-Gąsior

Jakub Lach

Marcin Słomka

Jaroslaw Dziadek

Katarzyna Dzitko

Przemyslaw Plocinski

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