Jaroslaw Dziadek

Prof.

Polish Academy of Sciences

Poland

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Prof. Jaroslaw Dziadek is a faculty member at the Polish Academy of Sciences, located in Poland. His research focuses on the development of novel anti-infective agents, specifically targeting Toxoplasma gondii, influenza H1N1, and Mycobacterium tuberculosis. Recent publications highlight his work on quinoline derivatives and coumarin-linked compounds that inhibit key enzymes responsible for bacterial resistance and pathogenesis.

Articles (20)

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2024

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2020

Collaborators (13)

Adrian Bekier

Assistant Professor

Medical University of Lodz

POLAND

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Anna Żaczek

Ass. Prof.

Rzeszów University

POLAND

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Jakub Kryczka

Institute for Medical Biology

POLAND

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Radoslaw Bednarek

assistant professor

Medical University of Lodz

POLAND

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Katarzyna Krysztopa-Grzybowska

National Institute of Public Health

POLAND

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Wojciech Rypniewski

Professor

Institute of Bioorganic Chemistry Polish Academy of Sciences

POLAND

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Justyna Gatkowska

Associate Professor

University of Łódź

POLAND

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Malwina Kawka

University of Łódź

POLAND

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Jakub Lach

University of Łódź

POLAND

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Marcin Słomka

University of Łódź

POLAND

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Bozena Dziadek

academic teacher; researcher/PhD; Associate professor

University of Łódź

POLAND

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Katarzyna Dzitko

Deputy Dean of the Faculty of Biology and Environmental Protection / PhD, DSc, Assoc. Prof. (ENG) dr hab. prof. nadzw. UŁ (PL) / Director of the BioMedChem Doctoral School of the UL and Lodz Institutes of the Polish Academy of Science

University of Łódź

POLAND

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Przemyslaw Plocinski

adjunct professor

University of Łódź

POLAND

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Jaroslaw Dziadek

Research Interests

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Articles (20)

The whole genome sequence of Polish vaccine strain Mycobacterium bovis BCG Moreau

MnoSR removal in <i>Mycobacterium smegmatis</i> triggers broad transcriptional response to 1,3-propanediol and glucose as sole carbon sources.

New coumarin linked thiazole derivatives as antimycobacterial agents: Design, synthesis, enoyl acyl carrier protein reductase (InhA) inhibition and molecular modeling

Identification of new anti-mycobacterial agents based on quinoline-isatin hybrids targeting enoyl acyl carrier protein reductase (InhA)

Identification of Coumarin-Chalcone and Coumarin-Pyrazoline Derivatives as Novel Anti-Toxoplasma gondii Agents

Discovery of new quinoline derivatives bearing 1-aryl-1,2,3-triazole motif as influenza H1N1 virus neuraminidase inhibitors

Identification of 2-(N-aryl-1,2,3-triazol-4-yl) quinoline derivatives as antitubercular agents endowed with InhA inhibitory activity

Benzenesulfonohydrazide-tethered non-fused and fused heterocycles as potential anti-mycobacterial agents targeting enoyl acyl carrier protein reductase (InhA) with antibiofilm activity

Design, synthesis and computational studies of new azaheterocyclic coumarin derivatives as anti-<i>Mycobacterium tuberculosis</i> agents targeting enoyl acyl carrier protein reductase (InhA)

Depletion of tRNA CCA ‑ adding enzyme in Mycobacterium tuberculosis leads to polyadenylation of transcripts and precursor tRNAs

4-Arylthiosemicarbazide Derivatives as Toxoplasmic Aromatic Amino Acid Hydroxylase Inhibitors and Anti-inflammatory Agents

Imidazole-Thiosemicarbazide Derivatives as Potent Anti-Mycobacterium tuberculosis Compounds with Antibiofilm Activity

Mycobacterium tuberculosis Binds Human Serum Amyloid A, and the Interaction Modulates the Colonization of Human Macrophages and the Transcriptional Response of the Pathogen

Cholesterol-dependent transcriptome remodeling reveals new insight into the contribution of cholesterol to Mycobacterium tuberculosis pathogenesis.

Dissecting the RecA-(In)dependent Response to Mitomycin C in Mycobacterium tuberculosis Using Transcriptional Profiling and Proteomics Analyses

ATP-Dependent Ligases and AEP Primases Affect the Profile and Frequency of Mutations in Mycobacteria under Oxidative Stress

Lsr2 and Its Novel Paralogue Mediate the Adjustment of Mycobacterium smegmatis to Unfavorable Environmental Conditions

Cobalamin is present in cells of non-tuberculous mycobacteria, but not in Mycobacterium tuberculosis.

Early Drug Development and Evaluation of Putative Antitubercular Compounds in the -Omics Era

Novel Isoniazid-Carborane Hybrids Active In Vitro against Mycobacterium tuberculosis

Collaborators (13)

Adrian Bekier

Anna Żaczek

Jakub Kryczka

Radoslaw Bednarek

Katarzyna Krysztopa-Grzybowska

Wojciech Rypniewski

Justyna Gatkowska

Malwina Kawka

Jakub Lach

Marcin Słomka

Bozena Dziadek

Katarzyna Dzitko

Przemyslaw Plocinski

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