Brent Stockwell

Professor and Chair

Columbia University

United States

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About

Brent Stockwell is a Professor and Chair at Columbia University in the United States. His research focuses on a range of areas including the mechanisms of cell death in cancer, ferroptosis, and the identification of novel therapeutic targets through innovative screening methods. Notable recent articles include explorations of p53 pathways, neuronal development, and cancer treatment strategies.

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Collaborators (9)

Jason Tchieu

Assistant Professor

Cincinnati Children's Hospital Medical Center

UNITED STATES

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chunhua yu

University of Texas Southwestern Medical Center

UNITED STATES

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Michael Menden

University of Melbourne

AUSTRALIA

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Koutaro Yokote

Chiba University Graduate School of Medicine

JAPAN

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Ingeborg J. Klarenberg

University of Amsterdam

NETHERLANDS

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Wei Gu

Professor

Columbia University

UNITED STATES

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Hua Tian

Assistant Professor

University of Pittsburgh

UNITED STATES

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Zhiguo Zhang

Professor

Columbia University Irving Medical Center

UNITED STATES

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Hiroyuki Hosokawa

Associate professor

Tokai University School of Medicine

JAPAN

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Brent Stockwell

Research Interests

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About

Articles (22)

Danger zone: The balance between fat-driven health and death

p53-regulated non-apoptotic cell death pathways and their relevance in cancer and other diseases

Selective Small-Molecule Activator of Patient-Derived GPX4 Variant

GAS41 modulates ferroptosis by anchoring NRF2 on chromatin

Suppression of ferroptosis by vitamin A or radical-trapping antioxidants is essential for neuronal development

Identification of Potent ADCK3 Inhibitors through Structure-Based Virtual Screening

Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis

Spatial pharmacology using mass spectrometry imaging

APR-246 increases tumor antigenicity independent of p53

Multimodal imaging pipeline for molecular and cellular characterization of Liver tissue - HuBMAP TTD-Columbia/PSU

The therapeutic potential of targeting regulated non-apoptotic cell death

Cryosectioning fresh frozen tissues for multimodal imaging

Kinases Controlling Stability of the Oncogenic MYCN Protein

Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer

Dehydroascorbic acid sensitizes cancer cells to system xc- inhibition-induced ferroptosis by promoting lipid droplet peroxidation

A Study in Blue: Secondary Copper‐Rich Minerals and Their Associated Bacterial Diversity in Icelandic Lava Tubes

Small-molecule allosteric inhibitors of GPX4

Vitamin K: A new guardian against ferroptosis

GLS2 Is a Tumor Suppressor and a Regulator of Ferroptosis in Hepatocellular Carcinoma

DESI imaging mass spectrometry on liver tissue

Machine Learning Classifies Ferroptosis and Apoptosis Cell Death Modalities with TfR1 Immunostaining

Characterization of a patient-derived variant of GPX4 for precision therapy

Collaborators (9)

Jason Tchieu

chunhua yu

Michael Menden

Koutaro Yokote

Ingeborg J. Klarenberg

Wei Gu

Hua Tian

Zhiguo Zhang

Hiroyuki Hosokawa

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