Brian Liau

Harvard University

United States

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Articles (10)

Year:

2023

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2023

Year:

2023

Year:

2023

Year:

2023

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2023

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2022

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2022

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2021

Year:

2021

Collaborators (4)

Megan Jin Rae Yeo

Harvard University

UNITED STATES

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Peter van Galen

Assistant Professor

Brigham and Women's Hospital and Harvard Medical School

UNITED STATES

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Fadi Najm

Broad Institute

UNITED STATES

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Sichen Shao

Associate Professor

Harvard Medical School

UNITED STATES

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Brian Liau

Research Interests

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Articles (10)

Base Editor Scanning Reveals Activating Mutations of DNMT3A

Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma

Base editor screens for in situ mutational scanning at scale

Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery

Base editor scanning charts the DNMT3A activity landscape

Chromatin complex dependencies reveal targeting opportunities in leukemia

Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery

Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue Degraders

Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation

Discovering new biology with drug-resistance alleles

Collaborators (4)

Megan Jin Rae Yeo

Peter van Galen

Fadi Najm

Sichen Shao

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