Peter van Galen

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Assistant Professor

Brigham and Women's Hospital and Harvard Medical School

United States

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About

Peter van Galen is an Assistant Professor at Brigham and Women's Hospital, affiliated with Harvard Medical School in the United States. His research primarily focuses on ageing, immune fitness, and cancer, with significant contributions to the understanding of hematopoietic stem cells through single-cell genomics. He has published extensively on topics including leukemia, immunotherapy, and novel methodologies for profiling hematopoietic activity.

Recent Grants

Grant: Close

Epigenetic mechanisms of stem cell expansion in the aging hematopoietic system

Open Date: 2021-01-01

Close Date: 2022-12-01

Grant: Close

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Genomics and Therapeutic Target Identification

Open Date: 2020-12-01

Close Date: 2023-11-01

Grant: Close

Targeting survival mechanisms of persistent acute myeloid leukemia cells

Open Date: 2020-02-01

Close Date: 2022-02-01

Grant: Close

Chromatin plasticity in TET2 driven clonal hematopoiesis

Open Date: 2020-02-01

Close Date: 2021-01-01

Grant: Close

The role of epigenetic plasticity in acute myeloid leukemia cell persistence

Open Date: 2019-08-01

Close Date: 2022-07-31

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Collaborators (9)

anne tierens

University Health Network

CANADA

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Hussein A. Abbas

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Meyling H. Cheok

FRANCE

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Brian Liau

Harvard University

UNITED STATES

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Laura Washburn

University of Pittsburgh Medical Center

UNITED STATES

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Fadi Najm

Broad Institute

UNITED STATES

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Elizabeth Mittendorf

Harvard University

UNITED STATES

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Nina Cabezas Wallscheid

Full professor

ETH Zurich

SWITZERLAND

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Joerg Buescher

Head of Metabolomics Core Facility

Max Planck Institute of Immunobiology and Epigenetics

GERMANY

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Peter van Galen

Research Interests

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About

Recent Grants

Articles (19)

Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction: a preclinical study

Ageing, immune fitness and cancer

The PERKs of ER homeostasis for hematopoietic stem cells

Insights into Leukemia from Single-Cell Genomics

Protocol for mitochondrial variant enrichment from single-cell RNA sequencing using MAESTER

Oncogene-induced TIM-3 ligand expression dictates susceptibility to anti–TIM-3 therapy in mice

Spectral Flow Cytometry Methods and Pipelines for Comprehensive Immunoprofiling of Human Peripheral Blood and Bone Marrow

New frameworks for hematopoiesis derived from single-cell genomics

Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation

Targetable leukaemia dependency on noncanonical PI3Kγ signalling

Chromatin complex dependencies reveal targeting opportunities in leukemia

Mutation signatures reveal clonal evolution

Suppression of allograft rejection by regulatory B cells generated via toll-like receptor signaling

WAT3R: recovery of T-cell receptor variable regions from 3′ single-cell RNA-sequencing

Rise of the Clones: Myelodysplastic Syndrome to Secondary Acute Myeloid Leukemia

Clonal barcoding with qPCR detection enables live cell functional analyses for cancer research

A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia

Plasticity and immune evasion in childhood ALL

Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells

Collaborators (9)

anne tierens

Hussein A. Abbas

Meyling H. Cheok

Brian Liau

Laura Washburn

Fadi Najm

Elizabeth Mittendorf

Nina Cabezas Wallscheid

Joerg Buescher

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