C Simon Herrington

Professor

University of Edinburgh

United Kingdom

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About

Professor C Simon Herrington is a faculty member at the University of Edinburgh, UK. His research focuses on ovarian cancer, including risk stratification, molecular pathology, and treatment responses. Recent articles highlight his work on prognostic markers, genomic analysis, and clinical trials aimed at improving patient outcomes in gynecological cancers.

Articles (26)

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2025

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2022

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2022

Collaborators (15)

Charlie Gourley

University of Edinburgh

UNITED KINGDOM

C Simon Herrington

Research Interests

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About

Articles (26)

Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer.

Oxford Classic-defined EMT risk stratification of High Grade Serous Ovarian cancer for guiding treatment decisions

Combined genomic and molecular analysis defines prognostic markers of relapse in stage IA-IC1 clear cell ovarian carcinoma

Antibody drug conjugate targets are highly differentially expressed across the major types of ovarian cancer

Response to letter RE: Somatic BRCA1/2 mutations are associated with a similar survival advantage to their germline counterparts in tubo-ovarian high grade serous carcinoma

Pembrolizumab in Patients With Advanced Clear Cell Gynecological Cancer: A Phase 2 Nonrandomized Clinical Trial.

High throughput screening identifies dasatinib as synergistic with trametinib in low grade serous ovarian carcinoma.

FANCD2 expression affects platinum response and further characteristics of high grade serous ovarian cancer in cells with different genetic backgrounds

Whole exome sequencing reveals diverse genomic relatedness between paired concurrent endometrial and ovarian carcinomas

The survival benefit associated with complete macroscopic resection in epithelial ovarian cancer is histotype-specific

Ovarian carcinosarcoma is highly aggressive compared to other ovarian cancer histotypes

RFWD3 modulates response to platinum chemotherapy and promotes cancer associated phenotypes in high grade serous ovarian cancer.

Closing the loop – the role of pathologists in digital and computational pathology research

Compartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma

Clinical research in endometrial cancer: consensus recommendations from the Gynecologic Cancer InterGroup.

An overview of the molecular pathology of ovarian carcinomas

Deceptive pattern of cervical stromal invasion from an endometrioid endometrial carcinoma

Debiased ambient vibrations optical coherence elastography to profile cell, organoid and tissue mechanical properties

Whole exome sequencing of low grade serous ovarian carcinoma identifies genomic events associated with clinical outcome.

Distinct histopathological features are associated with molecular subtypes and outcome in low grade serous ovarian carcinoma.

Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial.

Recent Advances in Pathology: the 2022 Annual Review Issue of The Journal of Pathology

Ovarian carcinosarcoma is a distinct form of ovarian cancer with poorer survival compared to tubo-ovarian high-grade serous carcinoma

Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup

Multiomic characterisation of high grade serous ovarian carcinoma enables high resolution patient stratification.

Improving the Diagnosis of Endometrial Hyperplasia Using Computerized Analysis and Immunohistochemical Biomarkers

Collaborators (15)

Charlie Gourley

Edward Tobias

pierre bagnaninchi

Austin Miller

Sarah Waters

Hannah Kim

Peter Bankhead

Robert L Hollis

Christoph Grimm

Yvonne Reinwald

Daniel Field

Nischalan Pillay

Philip Coates

William Cross

Feras Abu Saadeh

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