Carles Galdeano
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Serra Hunter Lecturer professor
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About
Carles Galdeano is a Serra Hunter Lecturer at the Universitat de Barcelona, Spain. His research focuses on drug discovery, particularly targeting E3 ligases, amyloid-related diseases, and the development of multitarget anti-Alzheimer drugs. Recent work includes investigations into neuroinflammation in Parkinson’s disease and the pharmacological validation of novel anticancer compounds.
Recent Grants
Grant: Close
First-in-class treatment for Alzheimer’s Disease
Open Date: 2017-09-01
Close Date: 2019-06-01
Grant: Close
Beatriu de de Pinos B
Open Date: 2015-09-01
Close Date: 2017-08-01
Grant: Close
Marie Curie-orthoPROTACS
Open Date: 2013-04-01
Close Date: 2015-04-01
Grant: Close
EMBO Short-Term Fellowship
Open Date: 2012-06-01
Close Date: 2012-08-01
Grant: Close
Grants for research outside Catalonia (BE 2010)
Open Date: 2011-04-01
Close Date: 2011-06-01
Articles (6)
Year:
2025
Proximity-induced pharmacology (PIP) for amyloid-related diseases is a cutting-edge approach to treating conditions such as Alzheimer’s disease and other forms of dementia. By bringing small molecules close to amyloid-related proteins, these molecules can induce a plethora of effects that can break down pathogenic proteins and reduce the buildup of plaques. One of the most promising aspects of this drug discovery modality is that it can be used to target specific types of amyloid proteins, such as the beta-amyloid protein that is commonly associated with Alzheimer’s disease. This level of specificity could allow for more targeted and effective treatments. With ongoing research and development, it is hoped that these treatments can be refined and optimized to provide even greater benefits to patients. As our understanding of the underlying mechanisms of these diseases continues to grow, proximity-induced pharmacology treatments may become an increasingly important tool in the fight against dementia and other related conditions.
Year:
2024
Year:
2022
Year:
2021
Year:
2020
Year:
2020
Collaborators (4)
Diego Muñoz-Torrero
Full Professor of Organic & Medicinal Chemistry
University of Barcelona
Raimon Sabate
University of Barcelona
F. Javier Pérez-Areales
Assistant Professor
University of Barcelona
Alba Espargaró
Lecturer
University of Barcelona
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