Carlos Rogerio de Figueiredo

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Adjunct Professor/ Academy Research Fellow

University of Turku

Finland

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About

Carlos Rogerio de Figueiredo is an Adjunct Professor and Academy Research Fellow at the University of Turku, Finland. His research focuses on immunotherapy and tumor immunology, with recent publications addressing topics such as immune checkpoint resistance, tumor microenvironments, and novel biomarkers in melanoma and uveal melanoma. His work explores integrative systems immunology approaches and the role of epigenetic factors in cancer resistance mechanisms.

Recent Grants

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Targeting myeloid biomarkers for prognosis and immunotherapy of metastatic melanoma.

Open Date: 2021-05-01

Close Date: 2024-05-01

Grant: Close

Targeting myeloid pathway-axis in metastatic melanoma – mechanisms, prognostication and therapeutic opportunities

Open Date: 2020-09-01

Close Date: 2025-09-01

Grant: Close

Characterisation of the tumour- immune microenvironment in metastatic uveal melanoma

Open Date: 2018-01-01

Close Date: 2020-01-01

Grant: Close

Evaluation of tumour associated macrophages M1 and M2 in response to the anti-tumour C36L1 peptide

Open Date: 2016-07-01

Close Date: 2017-07-01

Grant: Close

Mechanism of action of the peptide C36L1, a microtubule depolymerization agent, in the activation of dendritic cells and metastatic melanoma therapy.

Open Date: 2015-04-01

Close Date: 2016-05-01

Articles (10)

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2025

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2024

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2023

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2023

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2023

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2020

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2020

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2020

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2020

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2020

Collaborators (6)

Tero Aittokallio

University of Helsinki

FINLAND

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Sarah E. Coupland

University of Liverpool

UNITED KINGDOM

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Joseph Slupsky

Professor

University of Liverpool

UNITED KINGDOM

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Roosa Kallionpää

University of Turku

FINLAND

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Judy M. Coulson

University of Liverpool

UNITED KINGDOM

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Otto Pulkkinen

University of Helsinki

FINLAND

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Carlos Rogerio de Figueiredo

Research Interests

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About

Recent Grants

Articles (10)

PRIME: An integrative systems immunology approach to predict anti-PD1 responses and discover new targets for melanoma immunotherapy

TIMP-1 is an activator of MHC-I expression in myeloid dendritic cells with implications for tumor immunogenicity

Epigenetic control of CD1D expression as a mechanism of resistance to immune checkpoint therapy in poorly immunogenic melanomas

Novel prognostication biomarker adipophilin reveals a metabolic shift in uveal melanoma and new therapeutic opportunities.

Resistance to immune checkpoint therapies by tumour-induced T-cell desertification and exclusion: key mechanisms, prognostication and new therapeutic opportunities

Transcriptome Profiling Reveals New Insights into the Immune Microenvironment and Upregulation of Novel Biomarkers in Metastatic Uveal Melanoma.

New tools to prevent cancer growth and spread: a 'Clever' approach.

Identification of very small cancer stem cells expressing hallmarks of pluripotency in B16F10 melanoma cells and their reoccurrence in B16F10-derived clones.

Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development.

Applying Single-Cell Technology in Uveal Melanomas: Current Trends and Perspectives for Improving Uveal Melanoma Metastasis Surveillance and Tumor Profiling.

Collaborators (6)

Tero Aittokallio

Sarah E. Coupland

Joseph Slupsky

Roosa Kallionpää

Judy M. Coulson

Otto Pulkkinen

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