Tero Aittokallio

University of Helsinki

Finland

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Articles (29)

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2022

Collaborators (39)

Mariliina Arjama

University of Helsinki

FINLAND

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Javeed Iqbal

Professor,

University of Nebraska Medical Center

UNITED STATES

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Vilja Pietiäinen

University of Helsinki

FINLAND

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Christina Wagner

University of Veterinary Medicine Vienna

AUSTRIA

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Ella Karjalainen

Institute for Molecular Medicine Finland

FINLAND

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Emmy Verschuren

University of Helsinki

FINLAND

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Heini Lassus

University of Helsinki

FINLAND

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Susanna Miettinen

Professor, Head of the Adult Stem Cell Group

University of Tampere

FINLAND

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Kjetil Tasken

Professor

University of Oslo

NORWAY

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Stefan Hüttelmaier

Martin Luther University Halle-Wittenberg

GERMANY

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Swapnil Potdar

University of Helsinki

FINLAND

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Kimmo Porkka

University of Helsinki

FINLAND

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Stephen J. Polyak

University of Washington

UNITED STATES

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Mark Zimmerman

Dana-Farber Cancer Institute

UNITED STATES

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Kaisa Joki

University of Turku

FINLAND

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Lukas Kenner

Guest Professor

Umeå University

SWEDEN

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Manuela Zucknick

Professor in Biostatistics, Director of the Oslo Centre for Biostatistics and Epidemiology

University of Oslo

NORWAY

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Shady Adnan Awad

University of Oxford

UNITED KINGDOM

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Jani Saarela

University of Helsinki

FINLAND

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Daniela Ungureanu

Associate Prof. (tenure)

University of Oulu

FINLAND

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Markus Vähä-Koskela

Coordinator of the FIMM professional postdoctoral career development programme

University of Helsinki

FINLAND

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Caroline Heckman

University of Helsinki

FINLAND

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Aleksandr Ianevski

University of Helsinki

FINLAND

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Astrid Murumägi

University of Helsinki

FINLAND

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Sanna Timonen

University of Helsinki

FINLAND

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Carlos Rogerio de Figueiredo

Adjunct Professor/ Academy Research Fellow

University of Turku

FINLAND

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Ziaurrehman Tanoli

University of Helsinki

FINLAND

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Sampsa Hautaniemi

University of Helsinki

FINLAND

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Kerstin Becker

University of Cologne

GERMANY

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Sarah E. Coupland

University of Liverpool

UNITED KINGDOM

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Johanna Hynninen

Deputy chief physician, Gynecologic oncologist

Helsinki University Hospital

FINLAND

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Satu Mustjoki

University of Helsinki

FINLAND

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Krister Wennerberg

Københavns Universitet

DENMARK

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Yanping Yin

Oslo University Hospital

NORWAY

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Diaaeldin I. Abdallah

Professor - Chemistry

Humber College

CANADA

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Tanja Ruokoranta

University of Helsinki

FINLAND

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Teemu Daniel Laajala

Docent (Associate / Adjunct Professor)

University of Turku

FINLAND

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Juho Miettinen

University of Helsinki

FINLAND

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Zoltan Kalo

Professor of Health Economics

Semmelweis University

HUNGARY

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Tero Aittokallio

Research Interests

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Articles (29)

High-throughput drug screening identifies SMAC mimetics as enhancers of NK-cell cytotoxicity in chronic myeloid leukemia

Protein Profiles Predict Treatment Responses to the PI3K Inhibitor Umbralisib in Patients with Chronic Lymphocytic Leukemia

A Machine Learning–Based Strategy Predicts Selective and Synergistic Drug Combinations for Relapsed Acute Myeloid Leukemia

Computational drug repurposing: approaches, evaluation of in silico resources and case studies

Dual STAT3/STAT5 inhibition as a novel treatment strategy in T-prolymphocytic leukemia

Spatial artifact detection improves the reproducibility of drug screening experiments

Proteasome inhibition overcomes resistance to targeted therapies in B-cell malignancy models and in an index patient

Scaling up drug combination surface prediction

Validation guidelines for drug-target prediction methods

A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells

Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia

Robust scoring of selective drug responses for patient-tailored therapy selection

ScType enables fast and accurate cell type identification from spatial transcriptomics data

Attention-based approach to predict drug–target interactions across seven target superfamilies

Editorial overview–Artificial intelligence methodologies in structural biology

RepurposeDrugs: an interactive web-portal and predictive platform for repurposing mono- and combination therapies

Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia

Tutorial on survival modeling with applications to omics data

Dual specific STAT3/5 degraders effectively block acute myeloid leukemia and natural killer/T cell lymphoma.

Breeze 2.0

Drug response profiles in patient-derived cancer cells across histological subtypes of ovarian cancer

OSCAR: Optimal subset cardinality regression using the L0-pseudonorm with applications to prognostic modelling of prostate cancer

Systematic Literature Review of Economic Evaluations of Treatment Alternatives in Chronic Lymphocytic Leukemia.

The miR-141/200c-STAT4 Axis Contributes to Leukemogenesis by Enhancing Cell Proliferation in T-PLL

Resistance to immune checkpoint therapies by tumour-induced T-cell desertification and exclusion: key mechanisms, prognostication and new therapeutic opportunities

Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells

Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia

Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia

Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2

Collaborators (39)

Mariliina Arjama

Javeed Iqbal

Vilja Pietiäinen

Christina Wagner

Ella Karjalainen

Emmy Verschuren

Heini Lassus

Susanna Miettinen

Kjetil Tasken

Stefan Hüttelmaier

Swapnil Potdar

Kimmo Porkka

Stephen J. Polyak

Mark Zimmerman

Kaisa Joki

Lukas Kenner

Manuela Zucknick

Shady Adnan Awad

Jani Saarela

Daniela Ungureanu

Markus Vähä-Koskela

Caroline Heckman

Aleksandr Ianevski

Astrid Murumägi

Sanna Timonen

Carlos Rogerio de Figueiredo

Ziaurrehman Tanoli

Sampsa Hautaniemi

Kerstin Becker

Sarah E. Coupland

Johanna Hynninen

Satu Mustjoki

Krister Wennerberg

Yanping Yin

Diaaeldin I. Abdallah

Tanja Ruokoranta

Teemu Daniel Laajala

Juho Miettinen

Zoltan Kalo

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