Carmine Ostacolo

Associate Professor

University of Salerno

Italy

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Dr. Carmine Ostacolo is an Associate Professor at the University of Salerno, Italy. His research focuses on neuropharmacology, examining the neuroprotective potential of various compounds, including indole-based substances and endocannabinoid system interactions. He also investigates pharmacological innovations involving marine toxins and the discovery of modulators for voltage-gated potassium channels. His recent work includes the design and characterization of bioactive compounds with therapeutic applications, particularly in the context of neurological disorders and viral infections.

Articles (18)

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2024

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2021

Collaborators (29)

Krzysztof Pyrc

Professor

POLAND

Carmine Ostacolo

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Articles (18)

In Silico Methods for the Discovery of Kv7.2/7.3 Channels Modulators: A Comprehensive Review

Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization

Neuroprotective Potential of Indole-Based Compounds: A Biochemical Study on Antioxidant Properties and Amyloid Disaggregation in Neuroblastoma Cells

Exploring Endocannabinoid System: Unveiling New Roles in Modulating ER Stress

Voltage-Gated K+ Channel Modulation by Marine Toxins: Pharmacological Innovations and Therapeutic Opportunities

KCNT1 Channel Blockers: A Medicinal Chemistry Perspective

Novel pyrrole based CB2 agonists: New insights on CB2 receptor role in regulating neurotransmitters' tone

A Combination of Polymethoxyflavones from <i>Citrus sinensis</i> and Prenylflavonoids from <i>Humulus lupulus</i> Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation

Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis

In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents

New Frontiers on ER Stress Modulation: Are TRP Channels the Leading Actors?

In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening

N-4 Alkyl Cytosine Derivatives Synthesis: A New Approach

Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization

Lipid Nanoparticles Traverse Non-Corneal Path to Reach the Posterior Eye Segment: In Vivo Evidence

<span style="font-variant: small-caps">l</span>-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells

Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy

A Novel Vasoactive Peptide “PG1” from Buffalo Ice-Cream Protects from Angiotensin-Evoked High Blood Pressure

Collaborators (29)

Krzysztof Pyrc

Sebastiano Intagliata

Patrizia Diana

Alessia Bertamino

Vincenzo Vestuto

Asia Fernandez-Carvajal

Silvana Pedatella

Barbara Parrino

Maria Rita Bongiorno

Nicola Micale

Carmelo PUGLIA

Elena Novelli

Eleonora Venturini

Mario Felice Tecce

Anna Kula-Pacurar

Luisa Tesoriere

Mario Allegra

Pietro Campiglia

Camilla Pecoraro

Ana Jiménez Alesanco

Veronica DI SARNO

Emanuela Salviati

Ester Aso

Stefania Raimondo

Sonia Vega Sánchez

Mauro De Nisco

Paolo Blasi

Takumi Konno

Antonella D'ANNEO

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