Caroline Heckman

University of Helsinki

Finland

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Articles (10)

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2024

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2024

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2024

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2024

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2024

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2024

Collaborators (25)

Elham Gholizadeh

University of Helsinki

FINLAND

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Vilja Pietiäinen

University of Helsinki

FINLAND

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Susanna Miettinen

Professor, Head of the Adult Stem Cell Group

University of Tampere

FINLAND

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Nemo Koi Ikonen

University of Helsinki

FINLAND

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Swapnil Potdar

University of Helsinki

FINLAND

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Kimmo Porkka

University of Helsinki

FINLAND

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Mohieddin Jafari

University of Helsinki

FINLAND

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Tamara Jacqueline Luck

University of Helsinki

FINLAND

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Harri Kalevi Mustonen

University of Helsinki

FINLAND

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Jani Saarela

University of Helsinki

FINLAND

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Tero Aittokallio

University of Helsinki

FINLAND

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Markus Vähä-Koskela

Coordinator of the FIMM professional postdoctoral career development programme

University of Helsinki

FINLAND

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Lidia Moyano-Galceran

Københavns Universitet

DENMARK

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Mahesh Tambe

University of Helsinki

FINLAND

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Mika Kontro

University of Helsinki

FINLAND

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Philipp Sergeev

University of Helsinki

FINLAND

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Anna Vähärautio

University of Helsinki

FINLAND

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Krister Wennerberg

Københavns Universitet

DENMARK

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Anni Irmeli Nieminen

University of Helsinki

FINLAND

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Anniina Maria Tervi

University of Helsinki

FINLAND

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Markus Otto Hjalmar Ramste

University of Helsinki

FINLAND

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Tanja Ruokoranta

University of Helsinki

FINLAND

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Jukka Hiltunen

Chief Intellectual Property Counsel

FINLAND

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Juho Miettinen

University of Helsinki

FINLAND

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Esa Pitkänen

FINLAND

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Caroline Heckman

Research Interests

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Articles (10)

Targeting CD33+ acute myeloid leukemia with GLK-33, a lintuzumab-auristatin conjugate with a wide therapeutic window.

Genetic and functional analysis of Raynaud’s syndrome implicates loci in vasculature and immunity

Robust scoring of selective drug responses for patient-tailored therapy selection

Monosomy 7/del(7q) Cause Sensitivity to Inhibitors of Nicotinamide Phosphoribosyltransferase in Acute Myeloid Leukemia

Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling

Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones

Distinct molecular profiles and shared drug vulnerabilities in pancreatic metastases of renal cell carcinoma

Venetoclax triggers sublethal apoptotic signaling in venetoclax-resistant acute myeloid leukemia cells and induces vulnerability to PARP inhibition and azacitidine

Ex Vivo Venetoclax Sensitivity Predicts Clinical Response in Acute Myeloid Leukemia in the Prospective VenEx Trial

A menin-KMT2A inhibitor to overcome resistance

Collaborators (25)

Elham Gholizadeh

Vilja Pietiäinen

Susanna Miettinen

Nemo Koi Ikonen

Swapnil Potdar

Kimmo Porkka

Mohieddin Jafari

Tamara Jacqueline Luck

Harri Kalevi Mustonen

Jani Saarela

Tero Aittokallio

Markus Vähä-Koskela

Lidia Moyano-Galceran

Mahesh Tambe

Mika Kontro

Philipp Sergeev

Anna Vähärautio

Krister Wennerberg

Anni Irmeli Nieminen

Anniina Maria Tervi

Markus Otto Hjalmar Ramste

Tanja Ruokoranta

Jukka Hiltunen

Juho Miettinen

Esa Pitkänen

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