Caterina FATTORUSSO

Full Professor in Medicinal Chemistry

Università degli Studi di Napoli Federico II

Italy

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Professor Caterina Fattorusso is a Full Professor in Medicinal Chemistry at Università degli Studi di Napoli Federico II, Italy. Her research areas include the development of inhibitors targeting cysteine proteases, the exploration of allosteric modulation of the insulin-degrading enzyme, and novel anticancer agents for melanoma. She has also investigated the biological activity of nature-inspired compounds and their stereochemistry, as well as the modulation of proteasome activity through porphyrin derivatives.

Articles (15)

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2025

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (16)

Ferdinando Fiorino

University of Naples Federico II

ITALY

Caterina FATTORUSSO

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Articles (15)

1,2,4-Thiadiazolidin-3,5-Diones as Inhibitors of Cysteine Proteases

Electronic Circular Dichroism Detects Conformational Changes Associated with Proteasome Gating Confirmed Using AFM Imaging

Tetrasubstituted Pyrrole Derivative Mimetics of Protein–Protein Interaction Hot-Spot Residues: A Promising Class of Anticancer Agents Targeting Melanoma Cells

Role of Stereochemistry on the Biological Activity of Nature-Inspired 3-Br-Acivicin Isomers and Derivatives

Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells

The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design

A multidisciplinary approach disclosing unexplored Aflatoxin B1 roles in severe impairment of vitamin D mechanisms of action

Silybins are stereospecific regulators of the 20S proteasome

Modulation of the 20S Proteasome Activity by Porphyrin Derivatives Is Steered through Their Charge Distribution

Corrigendum to “Silybins are stereospecific regulators of the 20S proteasome” [Bioorgan. Med. Chem. 66 (2022) 116813] (Bioorganic &amp; Medicinal Chemistry (2022) 66, (S096808962200205X), (10.1016/j.bmc.2022.116813))

Hybrids between H<sub>2</sub>S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells

New Insights into the Structure–Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na<sup>+</sup>/Ca<sup>2+</sup> Exchanger Isoforms

Cooperative Binding of the Cationic Porphyrin Tris-T4 Enhances Catalytic Activity of 20S Proteasome Unveiling a Complex Distribution of Functional States

Antiplasmodial Activity of <i>p</i>-Substituted Benzyl Thiazinoquinone Derivatives and Their Potential against Parasitic Infections

Exploring the Photodynamic Properties of Two Antiproliferative Benzodiazopyrrole Derivatives

Collaborators (16)

Ferdinando Fiorino

SILVIA PARAPINI

Marialuisa Menna

Pawel Osmulski

Giuseppe Grasso

Paola Conti

Alessandro D'Urso

Carlo Irace

Chiara Borsari

Pietro Campiglia

Lucia Tamborini

Marialuisa Piccolo

Francesco Frecentese

MARINA GOBBO

ROBERTO PURRELLO

Carmela Dell'Aversano

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Corrigendum to “Silybins are stereospecific regulators of the 20S proteasome” [Bioorgan. Med. Chem. 66 (2022) 116813] (Bioorganic & Medicinal Chemistry (2022) 66, (S096808962200205X), (10.1016/j.bmc.2022.116813))