Chang Kweng Lim

Laboratory Chief

National Institute of Infectious Diseases

Japan

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Dr. Chang Kweng Lim is the Laboratory Chief at the National Institute of Infectious Diseases in Japan. His research areas include dengue virus diagnostics, development of neutralization tests for Japanese encephalitis virus, and studies on novel torque teno viruses in wildlife. He has contributed to significant findings related to vaccine-induced immunity and the pathogenicity of flaviviruses.

Articles (16)

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2025

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2022

Collaborators (4)

Shoichi Sakaguchi

Assistant professor

Osaka Medical and Pharmaceutical University

JAPAN

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Yuji Fujii

Assistant Professor

Nagasaki University

JAPAN

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Ryosuke Suzuki

Chief

National Institute of Infectious Diseases

JAPAN

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Satoshi Taniguchi

University of Tokyo

JAPAN

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Chang Kweng Lim

Research Interests

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Articles (16)

Dengue virus serotype 4 infection diagnosed not by rapid antigen test, but by real-time reverse transcription-PCR and enzyme-linked immunosorbent assay: A case report

Development of neutralization tests using single-round infectious particles and cytopathic effect as an alternative method for measuring antibody titers against Japanese encephalitis virus in national epidemiological surveillance program of vaccine-preventable diseases in Japan

Novel torque teno viruses infecting raccoon dogs (Nyctereutes procyonoides) and red foxes (Vulpes vulpes japonica)

A Single Dose of Yellow Fever Vaccine Provides Long-Term Immunity in Japanese Travelers

Evaluation of in vitro growth and pathogenicity in mice of intra-genotype chimeric strains of genotype IV Japanese encephalitis virus

Amino Acids at Positions 156 and 332 in the E Protein of the West Nile Virus Subtype Kunjin Virus Classical Strain OR393 Are Involved in Plaque Size, Growth, and Pathogenicity in Mice

Pathological and virological findings of type I interferon receptor knockout mice upon experimental infection with Heartland virus

Mutations in the 3′ non-coding region of a no-known vector flavivirus Yokose virus increased its replication ability in mosquito C6/36 cells

Correction: Tajima et al. Amino Acids at Positions 156 and 332 in the E Protein of the West Nile Virus Subtype Kunjin Virus Classical Strain OR393 Are Involved in Plaque Size, Growth, and Pathogenicity in Mice. Viruses 2024, 16, 1237

Analysis of cross-reactivity among flaviviruses using sera of patients with dengue showed the importance of neutralization tests with paired serum samples for the correct interpretations of serological test results for dengue

Japanese Encephalitis Virus Genotypes 1 and 3 Isolation in Kochi, Japan

Growth, Pathogenesis, and Serological Characteristics of the Japanese Encephalitis Virus Genotype IV Recent Strain 19CxBa-83-Cv

Identification of the corticotropin-releasing factor receptor 1 antagonists as inhibitors of Chikungunya virus replication using a Gaussia luciferase–expressing subgenomic replicon

Genetic Characterization of Human Rabies Vaccine Strain in Japan and Rabies Viruses Related to Vaccine Development from 1940s to 1980s

Susceptibility of Type I Interferon Receptor Knock-Out Mice to Heartland Bandavirus (HRTV) Infection and Efficacy of Favipiravir and Ribavirin in the Treatment of the Mice Infected with HRTV

Reverse Genetics System for Heartland Bandavirus: NSs Protein Contributes to Heartland Bandavirus Virulence

Collaborators (4)

Shoichi Sakaguchi

Yuji Fujii

Ryosuke Suzuki

Satoshi Taniguchi

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