Shoichi Sakaguchi

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Assistant professor

Osaka Medical and Pharmaceutical University

Japan

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About

Shoichi Sakaguchi is an Assistant Professor at Osaka Medical and Pharmaceutical University in Japan. His research primarily focuses on virology, including SARS-CoV-2, as well as the genetic characterization of viral pathogens in livestock. Recent publications include studies on mutation-tolerant inhibitors for SARS-CoV-2 and the isolation of novel bovine parechoviruses, reflecting his expertise in both viral morphology and pathogenic interactions. He is actively engaged in advancing RNA virus discovery and exploring the microbiota changes associated with gastric cancer.

Recent Grants

Grant: Close

ネコモルビリウイルスの持続感染に不完全ウイルスRNAが果たす役割の解明

Open Date: 2022-04-01

Close Date: 2025-03-31

Grant: Close

胃切除後障害の改善に向けた網羅的細菌叢変化の検討

Open Date: 2022-04-01

Close Date: 2025-03-31

Grant: Close

Studies on the mechanism of oral microbiome formation via microbiome analysis of pregnant women and their infants

Open Date: 2021-04-01

Close Date: 2024-03-31

Grant: Close

Construction of molecular evolution model for genes derived from endogenous retroviruses

Open Date: 2020-04-01

Close Date: 2023-03-31

Grant: Close

遺伝子操作系によるネコモルビリウイルスの分子クローンの樹立と細胞内侵入機構の解明

Open Date: 2020-04-01

Close Date: 2022-03-31

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Collaborators (15)

Christian Eggeling

Leibniz Institute of Photonic Technology

GERMANY

Shoichi Sakaguchi

Research Interests

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About

Recent Grants

Articles (20)

Structure-guided engineering of a mutation-tolerant inhibitor peptide against variable SARS-CoV-2 spikes

Consensus statement from the first RdRp Summit: advancing RNA virus discovery at scale across communities

NeoRdRp2 with improved seed data, annotations, and scoring

Electron Tomography as a Tool to Study SARS-CoV-2 Morphology

Isolation and genetic characterization of novel bovine parechoviruses from Japanese black cattle

A zebrafish gene with sequence similarities to human uromodulin and GP2 displays extensive evolutionary diversification among teleost and confers resistance to bacterial infection

Identification of multiple inter- and intra-genotype reassortment mammalian orthoreoviruses from Japanese black cattle in a beef cattle farm

Morphological analysis for two types of viral particles in vacuoles of SARS-CoV-2-infected cells

Prevalence and genetic diversity in bovine parechovirus infecting Japanese cattle.

The International Virus Bioinformatics Meeting 2023

Changes in salivary microbiota due to gastric cancer resection and its relation to gastric fluid microbiota

Identification of the corticotropin-releasing factor receptor 1 antagonists as inhibitors of Chikungunya virus replication using a Gaussia luciferase–expressing subgenomic replicon

Salivary Microbiota Associated with Peripheral Microvascular Endothelial Dysfunction.

Comparison of the gastric microbiome in Billroth I and Roux-en-Y reconstructions after distal gastrectomy

NeoRdRp: A Comprehensive Dataset for Identifying RNA-dependent RNA Polymerases of Various RNA Viruses from Metatranscriptomic Data

Characterization of Salivary Microbiota in Patients with Atherosclerotic Cardiovascular Disease: A Case-Control Study

Three-dimensional reconstruction by electron tomography for the application to ultrastructural analysis of SARS-CoV-2 particles

Genomic diversity and intragenic recombination of species C rotaviruses

First isolation and genomic characterization of bovine parechovirus from faecal samples of cattle in Japan

Characterization of salivary microbiota in elderly patients with type 2 diabetes mellitus: a matched case–control study

Collaborators (15)

Christian Eggeling

Fumiyoshi OKAZAKI

Tatiana Demina

Kei Kazama

Kato-kogoe Nahoko

Simon Dellicour

Ana Abecasis

Chang Kweng Lim

Ingrida Olendraite

Manja Marz

Artem Babaian

Kohei Taniguchi

Nobutaka Numoto

So Nakagawa

Makoto Nagai

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